Innovative approach to identify multigenomic and environmental interactions associated with birth defects in family-based hybrid designs.

Lou, Xiang-Yang; Hou, Ting-Ting; Liu, Shou-Ye; Xu, Hai-Ming; Lin, Feng; Tang, Xinyu; MacLeod, Stewart L; Cleves, Mario A; Hobbs, Charlotte A

Lou, Xiang-Yang; Hou, Ting-Ting; Liu, Shou-Ye; Xu, Hai-Ming; Lin, Feng; Tang, Xinyu; MacLeod, Stewart L; Cleves, Mario A; Hobbs, Charlotte A.

Afiliação

Lou XY; Department of Biostatistics, College of Public Health and Health Professions and College of Medicine, University of Florida, Gainesville, Florida, USA.
Hou TT; Department of Biostatistics, College of Public Health and Health Professions and College of Medicine, University of Florida, Gainesville, Florida, USA.
Liu SY; Institute of Bioinformatics and Institute of Crop Science, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, China.
Xu HM; Institute of Bioinformatics and Institute of Crop Science, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, China.
Lin F; Institute of Bioinformatics and Institute of Crop Science, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, China.
Tang X; Institute of Bioinformatics and Institute of Crop Science, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, China.
MacLeod SL; The US Food and Drug Administration, Silver Spring, Maryland, USA.
Cleves MA; Arkansas Children's Research Institute, Little Rock, Arkansas, USA.
Hobbs CA; Department of Pediatrics, Morsani College of Medicine, Health Informatics Institute, University of South Florida, Tampa, Florida, USA.

Genet Epidemiol ; 45(2): 171-189, 2021 03.

Article em En | MEDLINE | ID: mdl-32996630

Assuntos

Cardiopatias Congênitas; Modelos Genéticos; Estudos de Casos e Controles; Humanos; Polimorfismo de Nucleotídeo Único; Fatores de Risco

Palavras-chave

case-control family design; congenital heart defects; environmental factors; fetal genes; genetic association and linkage; interactions; maternal genes

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cardiopatias Congênitas / Modelos Genéticos Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Genet Epidemiol Assunto da revista: EPIDEMIOLOGIA / GENETICA MEDICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

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