MS-based metabolite analysis of two licorice chalcones in mice plasma, bile, feces, and urine after oral administration.

Wu, Jing; Zhong, Qiao-Qiao; Wang, Tian-Yun; Wang, Chen-Xiang; Du, Yan; Ji, Shuai; Wang, Liang; Guo, Meng-Zhe; Tang, Dao-Quan

Wu, Jing; Zhong, Qiao-Qiao; Wang, Tian-Yun; Wang, Chen-Xiang; Du, Yan; Ji, Shuai; Wang, Liang; Guo, Meng-Zhe; Tang, Dao-Quan.

Afiliação

Wu J; Department of Pharmaceutical Analysis, Jiangsu College of Nursing, Huai'an, China.
Zhong QQ; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, China.
Wang TY; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, China.
Wang CX; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, China.
Du Y; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, China.
Ji S; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, China.
Wang L; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, China.
Guo MZ; Department of Pharmaceutical Analysis, Xuzhou Medical University, Xuzhou, China.
Tang DQ; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, China.

Biomed Chromatogr ; 35(3): e4998, 2021 Mar.

Article em En | MEDLINE | ID: mdl-33037660

Assuntos

Chalcona/análogos & derivados; Chalconas/análise; Cromatografia Líquida/métodos; Glucosídeos/análise; Espectrometria de Massas em Tandem/métodos; Administração Oral; Animais; Bile/química; Chalcona/administração & dosagem; Chalcona/análise; Chalcona/química; Chalcona/farmacocinética; Chalconas/administração & dosagem; Chalconas/química; Chalconas/farmacocinética; Fezes/química; Glucosídeos/administração & dosagem; Glucosídeos/química; Glucosídeos/farmacocinética; Glycyrrhiza; Camundongos; Camundongos Endogâmicos C57BL

Palavras-chave

isoliquiritigenin, isoliquiritin, liquid chromatography coupled with quadrupole/time-of-flight mass spectrometry (LC-Q/TOF-MS/MS), metabolite, mouse

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Chalcona / Cromatografia Líquida / Chalconas / Espectrometria de Massas em Tandem / Glucosídeos Tipo de estudo: Guideline / Prognostic_studies Limite: Animals Idioma: En Revista: Biomed Chromatogr Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China

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