[Fundamental aspects of oncogenesis]. / Aspects fondamentaux du développement tumoral.
Bull Cancer
; 107(11): 1148-1160, 2020 Nov.
Article
em Fr
| MEDLINE
| ID: mdl-33039132
ABSTRACT
Tumorigenesis has traditionally been considered as a multi-step process involving the activation of oncogenes as well as the inactivation of tumor suppressor genes. However, the mechanisms driving cancer initiation and progression are not restricted to molecular alterations and instead should be viewed as a complex process that interfaces with the entire organism. This didactic review provides an integrated and global view of the key fundamental principles of cancer development.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Carcinogênese
Tipo de estudo:
Etiology_studies
Limite:
Humans
Idioma:
Fr
Revista:
Bull Cancer
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
França