Impact of treatment delay on survival of oral/oropharyngeal cancers: Results of a nationwide screening program.
Head Neck
; 43(2): 473-484, 2021 02.
Article
em En
| MEDLINE
| ID: mdl-33047420
ABSTRACT
BACKGROUND:
To assess the impact of treatment delay on survival of oral/oropharyngeal cancer (OSCC).METHODS:
We followed 5743 OSCCs between 2004 and 2009 from a population-based screening program and ascertained death until the end of 2012.RESULTS:
The hazard ratios (HRs) of mortality from OSCC were 1.46 (1.30-1.65) and 1.18 (1.04-1.33) in univariable and multivariable analyses, respectively, for treatment delay longer than 6 weeks compared with that shorter than 3 weeks. The corresponding figures were 1.12 (1.01-1.24) and 1.00 (0.91-1.11) for treatment delay between 3 and 6 weeks. Advancing age (1.01), higher stage (stage II 1.84, stage III 2.97, stage IV 6.33), cancer in tongue (1.37), or hard palate (1.63) had higher HR of mortality (P < .05). However, treatment at medical center had a lower mortality (0.83, 0.75-0.91) than local/regional hospital.CONCLUSIONS:
Treatment delay longer than 6 weeks for OSCCs detected via a population-based screening program had unfavorable survival.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Bucais
/
Neoplasias Orofaríngeas
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Risk_factors_studies
/
Screening_studies
Limite:
Humans
Idioma:
En
Revista:
Head Neck
Assunto da revista:
NEOPLASIAS
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Taiwan