Gypenosides attenuate retinal degeneration in a zebrafish retinitis pigmentosa model.

Alhasani, Reem Hasaballah; Zhou, Xinzhi; Biswas, Lincoln; Li, Xing; Reilly, James; Zeng, Zhihong; Shu, Xinhua

Alhasani, Reem Hasaballah; Zhou, Xinzhi; Biswas, Lincoln; Li, Xing; Reilly, James; Zeng, Zhihong; Shu, Xinhua.

Afiliação

Alhasani RH; Department of Biological and Biomedical Sciences, Glasgow Caledonian University, Glasgow, G4 0BA, United Kingdom; Department of Biology, Faculty of Applied Science, Umm Al-Qura University, Makkah, Saudi Arabia.
Zhou X; Department of Biological and Biomedical Sciences, Glasgow Caledonian University, Glasgow, G4 0BA, United Kingdom.
Biswas L; Department of Biological and Biomedical Sciences, Glasgow Caledonian University, Glasgow, G4 0BA, United Kingdom.
Li X; School of Basic Medical Sciences, Shaoyang University, Shaoyang, Hunan, 422000, PR China.
Reilly J; Department of Biological and Biomedical Sciences, Glasgow Caledonian University, Glasgow, G4 0BA, United Kingdom.
Zeng Z; College of Biological and Environmental Engineering, Changsha University, Changsha, Hunan, 410022, PR China. Electronic address: z20181201@ccsu.edu.cn.
Shu X; Department of Biological and Biomedical Sciences, Glasgow Caledonian University, Glasgow, G4 0BA, United Kingdom; Department of Vision Science, Glasgow Caledonian University, Glasgow, G4 0BA, United Kingdom; School of Basic Medical Sciences, Shaoyang University, Shaoyang, Hunan, 422000, PR China. El

Exp Eye Res ; 201: 108291, 2020 12.

Article em En | MEDLINE | ID: mdl-33049273

Assuntos

Estresse Oxidativo; Células Fotorreceptoras de Invertebrados/efeitos dos fármacos; Retina/efeitos dos fármacos; Retinose Pigmentar/tratamento farmacológico; Animais; Gynostemma; Imuno-Histoquímica; Células Fotorreceptoras de Invertebrados/metabolismo; Células Fotorreceptoras de Invertebrados/patologia; Extratos Vegetais/farmacologia; Espécies Reativas de Oxigênio/metabolismo; Retina/metabolismo; Retina/patologia; Retinose Pigmentar/metabolismo; Retinose Pigmentar/patologia; Rodopsina/metabolismo; Peixe-Zebra

Palavras-chave

Gypenosides; Photoreceptor death; RPGRIP1; Retinitis pigmentosa; Zebrafish

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Retina / Retinose Pigmentar / Células Fotorreceptoras de Invertebrados / Estresse Oxidativo Limite: Animals Idioma: En Revista: Exp Eye Res Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Arábia Saudita

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