Guttiferone K Exerts the Anti-inflammatory Effect on Mycobacterium Tuberculosis- (H37Ra-) Infected Macrophages by Targeting the TLR/IRAK-1 Mediated Akt and NF-<i>&#954;</i>B Pathway.

Zhang, Qingwen; Sun, Jinxia; Fu, Yan; He, Weigang; Li, Yinhong; Tan, Hongsheng; Xu, Hongxi; Jiang, Xin

Guttiferone K Exerts the Anti-inflammatory Effect on Mycobacterium Tuberculosis- (H37Ra-) Infected Macrophages by Targeting the TLR/IRAK-1 Mediated Akt and NF-κB Pathway.

Zhang, Qingwen; Sun, Jinxia; Fu, Yan; He, Weigang; Li, Yinhong; Tan, Hongsheng; Xu, Hongxi; Jiang, Xin.

Afiliação

Zhang Q; Center for Traditional Chinese Medicine and Immunology Research, School of Basic Medical Sciences, Shanghai University of Traditional Chinese Medicine, 201203 Shanghai, China.
Sun J; Shanghai Key Laboratory of Molecular Imaging, Shanghai University of Medicine & Health Sciences, 201318 Shanghai, China.
Fu Y; Center for Traditional Chinese Medicine and Immunology Research, School of Basic Medical Sciences, Shanghai University of Traditional Chinese Medicine, 201203 Shanghai, China.
He W; Center for Traditional Chinese Medicine and Immunology Research, School of Basic Medical Sciences, Shanghai University of Traditional Chinese Medicine, 201203 Shanghai, China.
Li Y; Center for Traditional Chinese Medicine and Immunology Research, School of Basic Medical Sciences, Shanghai University of Traditional Chinese Medicine, 201203 Shanghai, China.
Tan H; Center for Traditional Chinese Medicine and Immunology Research, School of Basic Medical Sciences, Shanghai University of Traditional Chinese Medicine, 201203 Shanghai, China.
Xu H; Clinical Research Center, Shanghai Jiao Tong University School of Medicine, 200240 Shanghai, China.
Jiang X; Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.

Mediators Inflamm ; 2020: 8528901, 2020.

Article em En | MEDLINE | ID: mdl-33100904

Assuntos

Anti-Inflamatórios/uso terapêutico; Benzofenonas/uso terapêutico; Quinases Associadas a Receptores de Interleucina-1/metabolismo; Macrófagos/efeitos dos fármacos; Macrófagos/metabolismo; Mycobacterium tuberculosis/efeitos dos fármacos; Mycobacterium tuberculosis/patogenicidade; NF-kappa B/metabolismo; Proteínas Proto-Oncogênicas c-akt/metabolismo; Animais; Western Blotting; Sobrevivência Celular/efeitos dos fármacos; Feminino; Imunoprecipitação; Camundongos; Células RAW 264.7

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Benzofenonas / NF-kappa B / Proteínas Proto-Oncogênicas c-akt / Quinases Associadas a Receptores de Interleucina-1 / Macrófagos / Anti-Inflamatórios / Mycobacterium tuberculosis Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Mediators Inflamm Assunto da revista: BIOQUIMICA / PATOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China

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