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KLHL22 maintains PD-1 homeostasis and prevents excessive T cell suppression.
Zhou, Xiao Albert; Zhou, Jiadong; Zhao, Long; Yu, Guihui; Zhan, Jun; Shi, Chanyi; Yuan, Ruoshi; Wang, Yan; Chen, Changfeng; Zhang, Wenjia; Xu, Donghao; Ye, Yingjiang; Wang, Weibin; Shen, Zhanlong; Wang, Wei; Wang, Jiadong.
Afiliação
  • Zhou XA; Department of Radiation Medicine, Institute of Systems Biomedicine, School of Basic Medical Sciences, Peking University Health Science Center, 100191 Beijing, China.
  • Zhou J; Department of Radiation Medicine, Institute of Systems Biomedicine, School of Basic Medical Sciences, Peking University Health Science Center, 100191 Beijing, China.
  • Zhao L; Department of Gastroenterological Surgery, Laboratory of Surgical Oncology, Beijing Key Laboratory of Colorectal Cancer Diagnosis and Treatment Research, Peking University People's Hospital, 100044 Beijing, China.
  • Yu G; Department of Radiation Medicine, Institute of Systems Biomedicine, School of Basic Medical Sciences, Peking University Health Science Center, 100191 Beijing, China.
  • Zhan J; Department of Anatomy, Histology, and Embryology, School of Basic Medical Sciences, Peking University Health Science Center, 100191 Beijing, China.
  • Shi C; Department of Radiation Medicine, Institute of Systems Biomedicine, School of Basic Medical Sciences, Peking University Health Science Center, 100191 Beijing, China.
  • Yuan R; Department of Radiation Medicine, Institute of Systems Biomedicine, School of Basic Medical Sciences, Peking University Health Science Center, 100191 Beijing, China.
  • Wang Y; Department of Immunology, School of Basic Medical Sciences, Peking University Health Science Center, 100191 Beijing, China.
  • Chen C; Department of Radiation Medicine, Institute of Systems Biomedicine, School of Basic Medical Sciences, Peking University Health Science Center, 100191 Beijing, China.
  • Zhang W; Department of Radiation Medicine, Institute of Systems Biomedicine, School of Basic Medical Sciences, Peking University Health Science Center, 100191 Beijing, China.
  • Xu D; Department of Machine Intelligence, School of Electronics Engineering and Computer Science, Peking University, 100871 Beijing, China.
  • Ye Y; Department of Gastroenterological Surgery, Laboratory of Surgical Oncology, Beijing Key Laboratory of Colorectal Cancer Diagnosis and Treatment Research, Peking University People's Hospital, 100044 Beijing, China.
  • Wang W; Department of Radiation Medicine, Institute of Systems Biomedicine, School of Basic Medical Sciences, Peking University Health Science Center, 100191 Beijing, China.
  • Shen Z; Department of Gastroenterological Surgery, Laboratory of Surgical Oncology, Beijing Key Laboratory of Colorectal Cancer Diagnosis and Treatment Research, Peking University People's Hospital, 100044 Beijing, China; shenzhanlong@pkuph.edu.cn wangwei83427@bjmu.edu.cn wangjd@bjmu.edu.cn.
  • Wang W; Department of Immunology, School of Basic Medical Sciences, Peking University Health Science Center, 100191 Beijing, China; shenzhanlong@pkuph.edu.cn wangwei83427@bjmu.edu.cn wangjd@bjmu.edu.cn.
  • Wang J; Department of Radiation Medicine, Institute of Systems Biomedicine, School of Basic Medical Sciences, Peking University Health Science Center, 100191 Beijing, China; shenzhanlong@pkuph.edu.cn wangwei83427@bjmu.edu.cn wangjd@bjmu.edu.cn.
Proc Natl Acad Sci U S A ; 117(45): 28239-28250, 2020 11 10.
Article em En | MEDLINE | ID: mdl-33109719
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T / Proteínas Adaptadoras de Transdução de Sinal / Receptor de Morte Celular Programada 1 / Homeostase Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T / Proteínas Adaptadoras de Transdução de Sinal / Receptor de Morte Celular Programada 1 / Homeostase Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China