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Characteristics of female lung cancer in Korea: analysis of Korean National Lung Cancer Registry.
Lim, Jeong Uk; Han, Solji; Kim, Ho Cheol; Choi, Chang Min; Jung, Chi Young; Cho, Deog Gon; Jeon, Jae Hyun; Lee, Jeong Eun; Ahn, Jin Seok; Kim, Yeongdae; Choi, Yoo-Duk; Suh, Yang-Gun; Kim, Jung-Eun; Won, Young-Joo; Kim, Young-Chul; Park, Chan Kwon; Kim, Seung Joon.
Afiliação
  • Lim JU; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
  • Han S; Department of Applied Statistics, Yonsei University, Seoul, Korea.
  • Kim HC; Department of Pulmonary and Critical Care Medicine, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea.
  • Choi CM; Department of Pulmonary and Critical Care Medicine, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea.
  • Jung CY; Department of Internal Medicine, Daegu Catholic University School of Medicine, Daegu, Korea.
  • Cho DG; Department of Thoracic & Cardiovascular Surgery, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea.
  • Jeon JH; Department of Thoracic and Cardiovascular Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seoul, Korea.
  • Lee JE; Division of Pulmonology Department of Internal Medicine, Chungnam National University, Daejeon, Korea.
  • Ahn JS; Department of Medicine, Samsung Medical Center, Sungkyunkwan University, Seoul, Korea.
  • Kim Y; Department of Cardiothoracic Surgery, Pusan National University Hospital, Pusan, Korea.
  • Choi YD; Department of Pathology, Chonnam National University, Hwasun Hospital, Hwasun, Korea.
  • Suh YG; Proton Therapy Center, Research Institute and Hospital, National Cancer Center, Goyang, Korea.
  • Kim JE; Cancer Registration and Statistics Branch, National Cancer Center, Goyang, Korea.
  • Won YJ; Cancer Registration and Statistics Branch, National Cancer Center, Goyang, Korea.
  • Kim YC; Department of Internal Medicine, Chonnam National University, Hwasun Hospital, Hwasun, Korea.
  • Park CK; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
  • Kim SJ; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
J Thorac Dis ; 12(9): 4612-4622, 2020 Sep.
Article em En | MEDLINE | ID: mdl-33145034
BACKGROUNDS: The present study evaluated Korean women with lung cancer and compared the clinical characteristics of ever-smoker and never-smoker groups using the National Lung Cancer Registry. METHODS: In affiliation with the Korean Central Cancer Registry, the Korean Association for Lung Cancer constructed a registry into which 10% of the lung cancer cases in Korea were registered. Female lung cancer patients with valid smoking history were evaluated. RESULTS: Among 735 female lung cancer patients, 643 (87.5%) were never-smokers and 92 (12.5%) were smokers. The median survival was significantly longer in the never-smoker group (28 vs. 14 months; P<0.001). Among 683 patients with non-small cell lung cancer (NSCLC), the never-smoker group showed significantly longer median survival (29 vs. 14 months; P=0.002) and a higher proportion of stage I cancer (40.3% vs. 25.7%; P<0.001). Survival analysis of the NSCLC patients showed that smoking status, receiving only supportive care, EGFR mutation status, lung cancer stage, and forced vital capacity (FVC) (%) were significantly associated with mortality in the multivariate analysis (P=0.025, HR 2.39, 95% CI: 1.12-5.11; P=0.017, HR 3.14, 95% CI: 1.22-8.06; P=0.033, HR 0.63, 95% CI: 0.41-0.96; P<0.001, HR 11.88, 95% CI: 5.79-24.38; P=0.002, HR 0.98, 95% CI: 0.96-0.99, respectively). CONCLUSIONS: In Korean women with NSCLC, smoking status, not receiving active anticancer treatment, EGFR mutation status, lung cancer stage, and pulmonary function were significantly associated with mortality.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Thorac Dis Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Thorac Dis Ano de publicação: 2020 Tipo de documento: Article