[Immunomorphological (light and electron microscopic) diagnosis of human squamous cell cancer using monoclonal antibodies]. / Immunomorfologicheskaia (sveto- i élektronno-mikroskopicheskaia) diagnostika ploskokletochnogo raka cheloveka s pomoshch'iu monoklonal'ny kh antitel.
Arkh Patol
; 49(8): 23-9, 1987.
Article
em Ru
| MEDLINE
| ID: mdl-3314802
ABSTRACT
It is shown with fluorescent and peroxidase labels for antibodies that the antigen to which the monoclonal antibody A-6/2 is directed, is a marker for cells of the basal stratified epithelium (basal-cell antigen). This antigen persists in squamous cell carcinomas of various sites and degrees of differentiation, but does not occur in tumors of other origins. With electron immunocytochemistry, the antigen was found to be located in tonofilaments and desmosomes of human squamous cell carcinoma. The A-6/2 monoclonal and basal-cell antigen may be used when developing immunomorphologic (light- or electronmicroscopic) procedures for histogenetic diagnosis of these carcinomas.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pele
/
Carcinoma de Células Escamosas
/
Anticorpos Monoclonais
/
Antígenos
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
Ru
Revista:
Arkh Patol
Ano de publicação:
1987
Tipo de documento:
Article