Point-of-Care Influenza Testing Impacts Clinical Decision, Patient Flow, and Length of Stay in Hospitalized Adults.
J Infect Dis
; 226(1): 97-108, 2022 08 12.
Article
em En
| MEDLINE
| ID: mdl-33151320
ABSTRACT
BACKGROUND:
Influenza is difficult to distinguish clinically from other acute respiratory infections. Rapid laboratory diagnosis can help initiate early effective antiviral treatment and isolation. Implementing a novel point-of-care test (POCT) for influenza in the emergency department (ED) could improve treatment and isolation strategies and reduce the length of stay (LOS).METHODS:
In a prospective, controlled observational cohort study, we enrolled patients admitted due to acute respiratory illness to 2 public hospitals in Bergen, Norway, one using a rapid POCT for influenza (nâ =â 400), the other (nâ =â 167) using conventional rapid laboratory-based assay.RESULTS:
Prevalence of influenza was similar in the 2 hospitals (154/400, 38% vs 38%, 63/167; Pâ =â .863). Most patients in both hospitals received antiviral (83% vs 81%; Pâ =â .703) and antibiotic treatment (72% vs 62%; Pâ =â .149). Isolation was more often initiated in ED in the hospital using POCT (91% vs 80%; Pâ =â .025). Diagnosis by POCT was associated with shorter hospital stay; old age, diabetes, cancer, and use of antibiotics, particularly broad-spectrum antibiotics, were associated with prolonged stay.CONCLUSIONS:
POCT implementation in ED resulted in improved targeted isolation and shorter LOS. Regardless of POCT use, most influenza patients received antivirals (>80%) and antibiotics (>69%).Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Influenza Humana
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Humans
Idioma:
En
Revista:
J Infect Dis
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Noruega