Recurrent Antineutrophil Cytoplasmic Antibody-Associated Vasculitis Induced by Levamisole-Adulterated Cocaine.
Am J Dermatopathol
; 43(6): 443-445, 2021 Jun 01.
Article
em En
| MEDLINE
| ID: mdl-33156021
ABSTRACT
ABSTRACT Levamisole, an anthelmintic and immunomodulatory drug, was withdrawn from the US market in 1999 due to adverse effects, including agranulocytosis and vasculitis. In recent years, levamisole has been used as a common cocaine adulterant, and its use has led to an autoimmune syndrome characterized by an antineutrophil cytoplasmic antibody-associated vasculitis presenting with necrotic retiform purpura on the face and extremities. We present a case of recurrent levamisole-induced vasculitis initially misdiagnosed as systemic lupus erythematosus to highlight this easily misdiagnosed entity and to demonstrate re-exposure leading to recurrent vasculitis with more extensive clinical manifestations.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Levamisol
/
Contaminação de Medicamentos
/
Cocaína
/
Vasculite Associada a Anticorpo Anticitoplasma de Neutrófilos
/
Lúpus Eritematoso Sistêmico
Tipo de estudo:
Diagnostic_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
Am J Dermatopathol
Ano de publicação:
2021
Tipo de documento:
Article