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In Vitro and In Silico Evaluation of Anticancer Activity of New Indole-Based 1,3,4-Oxadiazoles as EGFR and COX-2 Inhibitors.
Sever, Belgin; Altintop, Mehlika Dilek; Özdemir, Ahmet; Akalin Çiftçi, Gülsen; Ellakwa, Doha E; Tateishi, Hiroshi; Radwan, Mohamed O; Ibrahim, Mahmoud A A; Otsuka, Masami; Fujita, Mikako; Ciftci, Halil I; Ali, Taha F S.
Afiliação
  • Sever B; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskisehir 26470, Turkey.
  • Altintop MD; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskisehir 26470, Turkey.
  • Özdemir A; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskisehir 26470, Turkey.
  • Akalin Çiftçi G; Department of Biochemistry, Faculty of Pharmacy, Anadolu University, Eskisehir 26470, Turkey.
  • Ellakwa DE; Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Al-Azhar University, Cairo 11765, Egypt.
  • Tateishi H; Medicinal and Biological Chemistry Science Farm Joint Research Laboratory, School of Pharmacy, Kumamoto University, Kumamoto 862-0973, Japan.
  • Radwan MO; Medicinal and Biological Chemistry Science Farm Joint Research Laboratory, School of Pharmacy, Kumamoto University, Kumamoto 862-0973, Japan.
  • Ibrahim MAA; Department of Drug Discovery, Science Farm Ltd., Kumamoto 862-0976, Japan.
  • Otsuka M; Chemistry of Natural Compounds Department, Pharmaceutical and Drug Industries Research Division, National Research Centre, Dokki, Cairo 12622, Egypt.
  • Fujita M; Computational Chemistry Laboratory, Chemistry Department, Faculty of Science, Minia University, Minia 61519, Egypt.
  • Ciftci HI; Medicinal and Biological Chemistry Science Farm Joint Research Laboratory, School of Pharmacy, Kumamoto University, Kumamoto 862-0973, Japan.
  • Ali TFS; Department of Drug Discovery, Science Farm Ltd., Kumamoto 862-0976, Japan.
Molecules ; 25(21)2020 Nov 07.
Article em En | MEDLINE | ID: mdl-33171861
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxidiazóis / Inibidores de Ciclo-Oxigenase 2 / Indóis / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Molecules Assunto da revista: BIOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Turquia
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxidiazóis / Inibidores de Ciclo-Oxigenase 2 / Indóis / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Molecules Assunto da revista: BIOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Turquia