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Antipsychotic olanzapine-induced misfolding of proinsulin in the endoplasmic reticulum accounts for atypical development of diabetes.
Ninagawa, Satoshi; Tada, Seiichiro; Okumura, Masaki; Inoguchi, Kenta; Kinoshita, Misaki; Kanemura, Shingo; Imami, Koshi; Umezawa, Hajime; Ishikawa, Tokiro; Mackin, Robert B; Torii, Seiji; Ishihama, Yasushi; Inaba, Kenji; Anazawa, Takayuki; Nagamine, Takahiko; Mori, Kazutoshi.
Afiliação
  • Ninagawa S; Department of Biophysics, Graduate School of Science, Kyoto University, Kyoto, Japan.
  • Tada S; Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Okumura M; Frontier Research Institute for Interdisciplinary Sciences, Tohoku University, Sendai, Japan.
  • Inoguchi K; Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Kinoshita M; Frontier Research Institute for Interdisciplinary Sciences, Tohoku University, Sendai, Japan.
  • Kanemura S; Frontier Research Institute for Interdisciplinary Sciences, Tohoku University, Sendai, Japan.
  • Imami K; School of Science and Technology, Kwansei Gakuin University, Sanda, Japan.
  • Umezawa H; Department of Molecular and Cellular BioAnalysis, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan.
  • Ishikawa T; Department of Biophysics, Graduate School of Science, Kyoto University, Kyoto, Japan.
  • Mackin RB; Department of Biophysics, Graduate School of Science, Kyoto University, Kyoto, Japan.
  • Torii S; Department of Biomedical Sciences, Creighton University School of Medicine, Omaha, United States.
  • Ishihama Y; Laboratory of Secretion Biology, Institute for Molecular and Cellular Regulation, Gunma University, Maebashi, Japan.
  • Inaba K; Department of Molecular and Cellular BioAnalysis, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan.
  • Anazawa T; Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, Sendai, Japan.
  • Nagamine T; Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Mori K; Sunlight Brain Research Center, Yamaguchi, Japan.
Elife ; 92020 11 17.
Article em En | MEDLINE | ID: mdl-33198886
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proinsulina / Dobramento de Proteína / Diabetes Mellitus / Retículo Endoplasmático / Olanzapina Limite: Animals Idioma: En Revista: Elife Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Japão
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proinsulina / Dobramento de Proteína / Diabetes Mellitus / Retículo Endoplasmático / Olanzapina Limite: Animals Idioma: En Revista: Elife Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Japão