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The establishment of a novel high-throughput screening system using RNA-guided genome editing to identify chemicals that suppress aldosterone synthase expression.
Ito, Ryo; Morita, Masanobu; Nakano, Taichi; Sato, Ikuko; Yokoyama, Atsushi; Sugawara, Akira.
Afiliação
  • Ito R; Department of Molecular Endocrinology, Tohoku University Graduate School of Medicine, Sendai, Japan.
  • Morita M; Department of Environmental Medicine and Molecular Toxicology, Tohoku University Graduate School of Medicine, Sendai, Japan.
  • Nakano T; Department of Molecular Endocrinology, Tohoku University Graduate School of Medicine, Sendai, Japan.
  • Sato I; Department of Molecular Endocrinology, Tohoku University Graduate School of Medicine, Sendai, Japan.
  • Yokoyama A; Department of Molecular Endocrinology, Tohoku University Graduate School of Medicine, Sendai, Japan.
  • Sugawara A; Department of Molecular Endocrinology, Tohoku University Graduate School of Medicine, Sendai, Japan. Electronic address: akiras2i@med.tohoku.ac.jp.
Biochem Biophys Res Commun ; 534: 672-679, 2021 01 01.
Article em En | MEDLINE | ID: mdl-33220920
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Citocromo P-450 CYP11B2 / Ensaios de Triagem em Larga Escala / Edição de Genes Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Humans Idioma: En Revista: Biochem Biophys Res Commun Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Japão
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Citocromo P-450 CYP11B2 / Ensaios de Triagem em Larga Escala / Edição de Genes Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Humans Idioma: En Revista: Biochem Biophys Res Commun Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Japão