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An Engineered Antibody with Broad Protective Efficacy in Murine Models of SARS and COVID-19.
Rappazzo, C Garrett; Tse, Longping V; Kaku, Chengzi I; Wrapp, Daniel; Sakharkar, Mrunal; Huang, Deli; Deveau, Laura M; Yockachonis, Thomas J; Herbert, Andrew S; Battles, Michael B; O'Brien, Cecilia M; Brown, Michael E; Geoghegan, James C; Belk, Jonathan; Peng, Linghang; Yang, Linlin; Scobey, Trevor D; Burton, Dennis R; Nemazee, David; Dye, John M; Voss, James E; Gunn, Bronwyn M; McLellan, Jason S; Baric, Ralph S; Gralinski, Lisa E; Walker, Laura M.
Afiliação
  • Rappazzo CG; Adimab LLC, Lebanon, NH 03766, USA.
  • Tse LV; Department of Epidemiology, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Kaku CI; Adimab LLC, Lebanon, NH 03766, USA.
  • Wrapp D; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712, USA.
  • Sakharkar M; Adimab LLC, Lebanon, NH 03766, USA.
  • Huang D; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Deveau LM; Adimab LLC, Lebanon, NH 03766, USA.
  • Yockachonis TJ; Paul G. Allen School of Global Animal Health, Washington State University, Pullman, WA 99164, USA.
  • Herbert AS; U.S. Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA.
  • Battles MB; The Geneva Foundation, 917 Pacific Avenue, Tacoma, WA 98402, USA.
  • O'Brien CM; Adimab LLC, Lebanon, NH 03766, USA.
  • Brown ME; U.S. Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA.
  • Geoghegan JC; The Geneva Foundation, 917 Pacific Avenue, Tacoma, WA 98402, USA.
  • Belk J; Adimab LLC, Lebanon, NH 03766, USA.
  • Peng L; Adimab LLC, Lebanon, NH 03766, USA.
  • Yang L; Adimab LLC, Lebanon, NH 03766, USA.
  • Scobey TD; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Burton DR; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Nemazee D; Department of Epidemiology, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Dye JM; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Voss JE; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Gunn BM; Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA.
  • McLellan JS; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard, Cambridge, MA 02139, USA.
  • Baric RS; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Gralinski LE; U.S. Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA.
  • Walker LM; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
bioRxiv ; 2020 Nov 17.
Article em En | MEDLINE | ID: mdl-33236009
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: BioRxiv Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: BioRxiv Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos