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Concurrent Dexamethasone Limits the Clinical Benefit of Immune Checkpoint Blockade in Glioblastoma.
Iorgulescu, J Bryan; Gokhale, Prafulla C; Speranza, Maria C; Eschle, Benjamin K; Poitras, Michael J; Wilkens, Margaret K; Soroko, Kara M; Chhoeu, Chhayheng; Knott, Aine; Gao, Yan; Lim-Fat, Mary Jane; Baker, Gregory J; Bonal, Dennis M; Nguyen, Quang-Dé; Grant, Gareth R L; Ligon, Keith L; Sorger, Peter K; Chiocca, E Antonio; Anderson, Ana C; Kirschmeier, Paul T; Sharpe, Arlene H; Freeman, Gordon J; Reardon, David A.
Afiliação
  • Iorgulescu JB; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Gokhale PC; Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts.
  • Speranza MC; Experimental Therapeutics Core and Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Eschle BK; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Poitras MJ; Experimental Therapeutics Core and Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Wilkens MK; Experimental Therapeutics Core and Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Soroko KM; Experimental Therapeutics Core and Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Chhoeu C; Experimental Therapeutics Core and Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Knott A; Experimental Therapeutics Core and Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Gao Y; Experimental Therapeutics Core and Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Lim-Fat MJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Baker GJ; Center for Neuro-Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Bonal DM; Department of Systems Biology, Harvard Medical School, Boston, Massachusetts.
  • Nguyen QD; Lurie Family Imaging Center, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Grant GRL; Lurie Family Imaging Center, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Ligon KL; University of Glasgow Medical School, Glasgow, Scotland, United Kingdom.
  • Sorger PK; Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts.
  • Chiocca EA; Department of Oncologic Pathology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Anderson AC; Broad Institute of Harvard and MIT, Cambridge, Massachusetts.
  • Kirschmeier PT; Department of Systems Biology, Harvard Medical School, Boston, Massachusetts.
  • Sharpe AH; Department of Neurosurgery, Brigham and Women's Hospital, Boston, Massachusetts.
  • Freeman GJ; Department of Neurology, Brigham and Women's Hospital, Boston, Massachusetts.
  • Reardon DA; Department of Immunology, Blavatnik Institute, Harvard Medical School and Evergrande Center for Immunologic Diseases, Harvard Medical School, Boston, Massachusetts.
Clin Cancer Res ; 27(1): 276-287, 2021 01 01.
Article em En | MEDLINE | ID: mdl-33239433
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Edema Encefálico / Neoplasias Encefálicas / Dexametasona / Glioblastoma / Inibidores de Checkpoint Imunológico Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Clin Cancer Res Assunto da revista: NEOPLASIAS Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Edema Encefálico / Neoplasias Encefálicas / Dexametasona / Glioblastoma / Inibidores de Checkpoint Imunológico Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Clin Cancer Res Assunto da revista: NEOPLASIAS Ano de publicação: 2021 Tipo de documento: Article