Class Switch Recombination Defects: impact on B cell maturation and antibody responses.

Renner, Ellen D; Krätz, Carolin E; Orange, Jordan S; Hagl, Beate; Rylaarsdam, Stacey; Notheis, Gundula; Durandy, Anne; Torgerson, Troy R; Ochs, Hans D

Renner, Ellen D; Krätz, Carolin E; Orange, Jordan S; Hagl, Beate; Rylaarsdam, Stacey; Notheis, Gundula; Durandy, Anne; Torgerson, Troy R; Ochs, Hans D.

Afiliação

Renner ED; University of Washington School of Medicine and Seattle Children's Research Institute, Seattle, WA, USA; Translational Immunology, Chair and Institute of Environmental Medicine, UNIKA-T, Technical University of Munich and Helmholtz Zentrum München, Munich, Augsburg, Germany.
Krätz CE; University Children's Hospital, Dr. von Haunersches Kinderspital, Ludwig Maximilian University, Munich, Germany; Translational Immunology, Chair and Institute of Environmental Medicine, UNIKA-T, Technical University of Munich and Helmholtz Zentrum München, Munich, Augsburg, Germany.
Orange JS; Columbia University, Department of Pediatrics, New York, United States of America.
Hagl B; University Children's Hospital, Dr. von Haunersches Kinderspital, Ludwig Maximilian University, Munich, Germany; Translational Immunology, Chair and Institute of Environmental Medicine, UNIKA-T, Technical University of Munich and Helmholtz Zentrum München, Munich, Augsburg, Germany.
Rylaarsdam S; University of Washington School of Medicine and Seattle Children's Research Institute, Seattle, WA, USA.
Notheis G; University Children's Hospital, Dr. von Haunersches Kinderspital, Ludwig Maximilian University, Munich, Germany; Translational Immunology, Chair and Institute of Environmental Medicine, UNIKA-T, Technical University of Munich and Helmholtz Zentrum München, Munich, Augsburg, Germany.
Durandy A; Laboratory of Human Lymphohaematopoiesis, INSERM UMR 1163, Imagine Institute, Paris, France; Université Paris Descartes-Sorbonne Paris Cité, Imagine Institute, Paris, France.
Torgerson TR; University of Washington School of Medicine and Seattle Children's Research Institute, Seattle, WA, USA.
Ochs HD; University of Washington School of Medicine and Seattle Children's Research Institute, Seattle, WA, USA. Electronic address: hans.ochs@seattlechildrens.org.

Clin Immunol ; 222: 108638, 2021 01.

Article em En | MEDLINE | ID: mdl-33276124

Assuntos

Linfócitos B/citologia; Bacteriófago phi X 174/imunologia; Switching de Imunoglobulina/genética; Switching de Imunoglobulina/imunologia; Síndromes de Imunodeficiência/genética; Síndromes de Imunodeficiência/imunologia; Adolescente; Adulto; Formação de Anticorpos/genética; Formação de Anticorpos/imunologia; Ligante de CD40/deficiência; Criança; Pré-Escolar; Feminino; Citometria de Fluxo; Humanos; Proteínas I-kappa B/genética; Imunização; Imunoglobulina D/imunologia; Imunoglobulina M/imunologia; Síndromes de Imunodeficiência/patologia; Memória Imunológica/genética; Memória Imunológica/imunologia; Lactente; Masculino; Membro 7 da Superfamília de Receptores de Fatores de Necrose Tumoral/imunologia

Palavras-chave

B cell development; Class switch recombination defect (CSRD); Clinical immunology; Hyper-IgM syndromes (HIGM); Immunodeficiencies

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos B / Bacteriófago phi X 174 / Switching de Imunoglobulina / Síndromes de Imunodeficiência Tipo de estudo: Prognostic_studies Limite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: Clin Immunol Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Alemanha

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google