Optogenetics: The Art of Illuminating Complex Signaling Pathways.

Shaaya, Mark; Fauser, Jordan; Karginov, Andrei V

Shaaya, Mark; Fauser, Jordan; Karginov, Andrei V.

Afiliação

Shaaya M; Department of Pharmacology and Regenerative Medicine, The University of Illinois at Chicago, College of Medicine, Chicago, Illinois.
Fauser J; Department of Pharmacology and Regenerative Medicine, The University of Illinois at Chicago, College of Medicine, Chicago, Illinois.
Karginov AV; Department of Pharmacology and Regenerative Medicine, The University of Illinois at Chicago, College of Medicine, Chicago, Illinois.

Physiology (Bethesda) ; 36(1): 52-60, 2021 01 01.

Article em En | MEDLINE | ID: mdl-33325819

ABSTRACT

ABSTRACT

Dissection of cell signaling requires tools that can mimic spatiotemporal dynamics of individual pathways in living cells. Optogenetic methods enable manipulation of signaling processes with precise timing and local control. In this review, we describe recent optogenetic approaches for regulation of cell signaling, highlight their advantages and limitations, and discuss examples of their application.

Assuntos

Optogenética; Transdução de Sinais

Palavras-chave

optogenetics; signaling

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Optogenética Idioma: En Revista: Physiology (Bethesda) Assunto da revista: FISIOLOGIA Ano de publicação: 2021 Tipo de documento: Article

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