CorGAT: a tool for the functional annotation of SARS-CoV-2 genomes.

ABSTRACT

SUMMARY: While over 200 000 genomic sequences are currently available through dedicated repositories, ad hoc methods for the functional annotation of SARS-CoV-2 genomes do not harness all currently available resources for the annotation of functionally relevant genomic sites. Here, we present CorGAT, a novel tool for the functional annotation of SARS-CoV-2 genomic variants. By comparisons with other state of the art methods we demonstrate that, by providing a more comprehensive and rich annotation, our method can facilitate the identification of evolutionary patterns in the genome of SARS-CoV-2. AVAILABILITYAND IMPLEMENTATION Galaxy.http//corgat.cloud.ba.infn.it/galaxy; software https//github.com/matteo14c/CorGAT/tree/Revision_V1; docker https//hub.docker.com/r/laniakeacloud/galaxy_corgat. SUPPLEMENTARY INFORMATION Supplementary data are available at Bioinformatics online.