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DNA Polymerase and Mismatch Repair Exert Distinct Microsatellite Instability Signatures in Normal and Malignant Human Cells.
Chung, Jiil; Maruvka, Yosef E; Sudhaman, Sumedha; Kelly, Jacalyn; Haradhvala, Nicholas J; Bianchi, Vanessa; Edwards, Melissa; Forster, Victoria J; Nunes, Nuno M; Galati, Melissa A; Komosa, Martin; Deshmukh, Shriya; Cabric, Vanja; Davidson, Scott; Zatzman, Matthew; Light, Nicholas; Hayes, Reid; Brunga, Ledia; Anderson, Nathaniel D; Ho, Ben; Hodel, Karl P; Siddaway, Robert; Morrissy, A Sorana; Bowers, Daniel C; Larouche, Valérie; Bronsema, Annika; Osborn, Michael; Cole, Kristina A; Opocher, Enrico; Mason, Gary; Thomas, Gregory A; George, Ben; Ziegler, David S; Lindhorst, Scott; Vanan, Magimairajan; Yalon-Oren, Michal; Reddy, Alyssa T; Massimino, Maura; Tomboc, Patrick; Van Damme, An; Lossos, Alexander; Durno, Carol; Aronson, Melyssa; Morgenstern, Daniel A; Bouffet, Eric; Huang, Annie; Taylor, Michael D; Villani, Anita; Malkin, David; Hawkins, Cynthia E.
Afiliação
  • Chung J; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Maruvka YE; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Sudhaman S; Institute of Medical Science, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
  • Kelly J; Massachusetts General Hospital Center for Cancer Research, Charlestown, Massachusetts.
  • Haradhvala NJ; Broad Institute of Harvard and MIT, Cambridge, Massachusetts.
  • Bianchi V; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Edwards M; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Forster VJ; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Nunes NM; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Galati MA; Massachusetts General Hospital Center for Cancer Research, Charlestown, Massachusetts.
  • Komosa M; Broad Institute of Harvard and MIT, Cambridge, Massachusetts.
  • Deshmukh S; Harvard Graduate Program in Biophysics, Harvard University, Cambridge, Massachusetts.
  • Cabric V; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Davidson S; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Zatzman M; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Light N; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Hayes R; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Brunga L; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Anderson ND; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Ho B; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Hodel KP; Institute of Medical Science, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
  • Siddaway R; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Morrissy AS; Department of Experimental Medicine, McGill University, Montreal, Quebec, Canada.
  • Bowers DC; The Research Institute of the McGill University Health Center, Montreal, Quebec, Canada.
  • Larouche V; Department of Paediatrics, University of Toronto, Toronto, Ontario, Canada.
  • Bronsema A; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Osborn M; Department of Paediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Cole KA; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Opocher E; Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
  • Mason G; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Thomas GA; Institute of Medical Science, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
  • George B; Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
  • Ziegler DS; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Lindhorst S; Department of Paediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Vanan M; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Yalon-Oren M; Department of Paediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Reddy AT; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Massimino M; Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
  • Tomboc P; Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
  • Van Damme A; Department of Biochemistry and Molecular Biology, Tulane Cancer Center, Tulane University of Medicine, New Orleans, Louisiana.
  • Lossos A; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Durno C; Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
  • Aronson M; Charbonneau Cancer Institute and Alberta Children's Hospital Research Institute, Calgary, Alberta, Canada.
  • Morgenstern DA; Department of Pediatrics and Harold C. Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center, Dallas, Texas.
  • Bouffet E; Pauline Allen Gill Center for Cancer and Blood Disorders, Children's Health, Dallas, Texas.
  • Huang A; Department of Pediatrics, Centre Mere-enfant Soleil du CHU de Quebec, CRCHU de Quebec, Universite Laval, Quebec City, Quebec, Canada.
  • Taylor MD; Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Villani A; Department of Haematology and Oncology, Women's and Children's Hospital, North Adelaide, South Australia, Australia.
  • Malkin D; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
  • Hawkins CE; Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.
Cancer Discov ; 11(5): 1176-1191, 2021 05.
Article em En | MEDLINE | ID: mdl-33355208
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Regulação Neoplásica da Expressão Gênica / Transformação Celular Neoplásica / DNA Polimerase Dirigida por DNA / Instabilidade de Microssatélites / Reparo de Erro de Pareamento de DNA / Neoplasias Limite: Humans Idioma: En Revista: Cancer Discov Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Canadá
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Regulação Neoplásica da Expressão Gênica / Transformação Celular Neoplásica / DNA Polimerase Dirigida por DNA / Instabilidade de Microssatélites / Reparo de Erro de Pareamento de DNA / Neoplasias Limite: Humans Idioma: En Revista: Cancer Discov Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Canadá