Insufficient thrombopoietin due to hepatic dysmature results in thrombocytopenia in small-for-gestational-age rats.

Takeshita, Satoru; Kakita, Hiroki; Toriuchi, Kohki; Aoki, Hiromasa; Ueda, Hiroko; Wakatsuki, Akihiko; Yamada, Yasumasa; Aoyama, Mineyoshi

Takeshita, Satoru; Kakita, Hiroki; Toriuchi, Kohki; Aoki, Hiromasa; Ueda, Hiroko; Wakatsuki, Akihiko; Yamada, Yasumasa; Aoyama, Mineyoshi.

Afiliação

Takeshita S; Department of Pathobiology, Nagoya City University Graduate School of Pharmaceutical Sciences, 3-1 Tanabe-dori, Mizoho-ku, Nagoya, Aichi, 467-8603, Japan.
Kakita H; Department of Perinatal and Neonatal Medicine, Aichi Medical University, 1-1 Yazakokarimata, Nagakute, Aichi, 480-1195, Japan.
Toriuchi K; Department of Pathobiology, Nagoya City University Graduate School of Pharmaceutical Sciences, 3-1 Tanabe-dori, Mizoho-ku, Nagoya, Aichi, 467-8603, Japan.
Aoki H; Department of Perinatal and Neonatal Medicine, Aichi Medical University, 1-1 Yazakokarimata, Nagakute, Aichi, 480-1195, Japan.
Ueda H; Department of Pathobiology, Nagoya City University Graduate School of Pharmaceutical Sciences, 3-1 Tanabe-dori, Mizoho-ku, Nagoya, Aichi, 467-8603, Japan.
Wakatsuki A; Department of Pathobiology, Nagoya City University Graduate School of Pharmaceutical Sciences, 3-1 Tanabe-dori, Mizoho-ku, Nagoya, Aichi, 467-8603, Japan.
Yamada Y; Department of Perinatal and Neonatal Medicine, Aichi Medical University, 1-1 Yazakokarimata, Nagakute, Aichi, 480-1195, Japan.
Aoyama M; Department of Obstetrics and Gynecology, Aichi Medical University, 1-1 Yazakokarimata, Nagakute, Aichi, 480-1195, Japan.

Br J Haematol ; 192(4): e105-e108, 2021 02.

Article em En | MEDLINE | ID: mdl-33403676

Assuntos

Fígado/fisiopatologia; Trombocitopenia/fisiopatologia; Trombopoetina/metabolismo; Animais; Animais Recém-Nascidos; Peso ao Nascer; Feminino; Hipertensão/complicações; Fígado/metabolismo; Gravidez; Complicações Cardiovasculares na Gravidez/etiologia; Ratos; Ratos Wistar; Trombocitopenia/etiologia; Trombocitopenia/metabolismo; Trombopoetina/análise

Palavras-chave

hypertensive disorders of pregnancy; romiplostim; small for gestational age infants; thrombocytopenia; thrombopoietin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Trombocitopenia / Trombopoetina / Fígado Tipo de estudo: Etiology_studies Limite: Animals / Pregnancy Idioma: En Revista: Br J Haematol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Japão

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