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Comparative analysis of the AIB1 interactome in breast cancer reveals MTA2 as a repressive partner which silences E-Cadherin to promote EMT and associates with a pro-metastatic phenotype.
Vareslija, Damir; Ward, Elspeth; Purcell, Siobhan P; Cosgrove, Nicola S; Cocchiglia, Sinéad; O'Halloran, Philip J; Charmsaz, Sara; Bane, Fiona T; Brett, Francesca M; Farrell, Michael; Cryan, Jane; Beausang, Alan; Hudson, Lance; Turnbul, Arran K; Dixon, J Michael; Hill, Arnold D K; Priedigkeit, Nolan; Oesterreich, Steffi; Lee, Adrian V; Sims, Andrew H; Redmond, Aisling M; Carroll, Jason S; Young, Leonie S.
Afiliação
  • Vareslija D; Endocrine Oncology Research Group, Department of Surgery, Royal College of Surgeons in Ireland, Dublin, Ireland. damirvareslija@rcsi.ie.
  • Ward E; Endocrine Oncology Research Group, Department of Surgery, Royal College of Surgeons in Ireland, Dublin, Ireland.
  • Purcell SP; Endocrine Oncology Research Group, Department of Surgery, Royal College of Surgeons in Ireland, Dublin, Ireland.
  • Cosgrove NS; Endocrine Oncology Research Group, Department of Surgery, Royal College of Surgeons in Ireland, Dublin, Ireland.
  • Cocchiglia S; Endocrine Oncology Research Group, Department of Surgery, Royal College of Surgeons in Ireland, Dublin, Ireland.
  • O'Halloran PJ; Department of Neurosurgery, National Neurosurgical Center, Beaumont Hospital, Dublin, Ireland.
  • Charmsaz S; Endocrine Oncology Research Group, Department of Surgery, Royal College of Surgeons in Ireland, Dublin, Ireland.
  • Bane FT; Endocrine Oncology Research Group, Department of Surgery, Royal College of Surgeons in Ireland, Dublin, Ireland.
  • Brett FM; Department of Neuropathology, National Neurosurgical Center, Beaumont Hospital, Dublin, Ireland.
  • Farrell M; Department of Neuropathology, National Neurosurgical Center, Beaumont Hospital, Dublin, Ireland.
  • Cryan J; Department of Neuropathology, National Neurosurgical Center, Beaumont Hospital, Dublin, Ireland.
  • Beausang A; Department of Neuropathology, National Neurosurgical Center, Beaumont Hospital, Dublin, Ireland.
  • Hudson L; Endocrine Oncology Research Group, Department of Surgery, Royal College of Surgeons in Ireland, Dublin, Ireland.
  • Turnbul AK; Breast Cancer Now Research Laboratories, Edinburgh, EH4 2XU, UK.
  • Dixon JM; Breast Cancer Now Research Laboratories, Edinburgh, EH4 2XU, UK.
  • Hill ADK; Endocrine Oncology Research Group, Department of Surgery, Royal College of Surgeons in Ireland, Dublin, Ireland.
  • Priedigkeit N; Department of Pharmacology and Chemical Biology, University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, PA, USA.
  • Oesterreich S; Department of Pharmacology and Chemical Biology, University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, PA, USA.
  • Lee AV; Department of Women's Cancer Research Center, Magee-Women's Research Institute, University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, PA, USA.
  • Sims AH; Department of Pharmacology and Chemical Biology, University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, PA, USA.
  • Redmond AM; Department of Women's Cancer Research Center, Magee-Women's Research Institute, University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, PA, USA.
  • Carroll JS; Department of Human Genetics, University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, PA, USA.
  • Young LS; Applied Bioinformatics of Cancer Group, University of Edinburgh Cancer Research UK Centre, MRC Institute of Genetics & Molecular Medicine, Western General Hospital, Edinburgh, UK.
Oncogene ; 40(7): 1318-1331, 2021 02.
Article em En | MEDLINE | ID: mdl-33420368
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Neoplasias da Mama / Caderinas / Coativador 3 de Receptor Nuclear / Histona Desacetilases Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Female / Humans Idioma: En Revista: Oncogene Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Irlanda
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Neoplasias da Mama / Caderinas / Coativador 3 de Receptor Nuclear / Histona Desacetilases Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Female / Humans Idioma: En Revista: Oncogene Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Irlanda