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Incidence and Impact of Parvovirus B19 Infection in Seronegative Solid Organ Transplant Recipients.
Rezahosseini, Omid; Ekenberg, Christina; Møller, Dina Leth; Sørensen, Søren Schwartz; Wareham, Neval Ete; Perch, Michael; Gustafsson, Finn; Rasmussen, Allan; Kirkby, Nikolai; Reekie, Joanne; Lundgren, Jens; Nielsen, Susanne Dam.
Afiliação
  • Rezahosseini O; Viro-immunology Research Unit, Department of Infectious Diseases 8632, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
  • Ekenberg C; Centre of Excellence for Health, Immunity, and Infections, Department of Infectious Diseases, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
  • Møller DL; Viro-immunology Research Unit, Department of Infectious Diseases 8632, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
  • Sørensen SS; Department of Nephrology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
  • Wareham NE; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
  • Perch M; Centre of Excellence for Health, Immunity, and Infections, Department of Infectious Diseases, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
  • Gustafsson F; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
  • Rasmussen A; Department of Cardiology, Section for Lung Transplantation, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
  • Kirkby N; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
  • Reekie J; Department of Cardiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
  • Lundgren J; Department of Surgical Gastroenterology and Transplantation, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
  • Nielsen SD; Department of Clinical Microbiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
J Infect Dis ; 224(5): 865-869, 2021 09 01.
Article em En | MEDLINE | ID: mdl-33458766
Routine monitoring of parvovirus B19 (B19V) the first 6 months posttransplantation was performed in 241 seronegative solid organ transplant (SOT) recipients. Incidence rates during the first month and the second to sixth months posttransplantation were 1.2 (95% confidence interval [CI], .33-3.2) and 0.21 (95% CI, .06-.57) per 100 recipients per month, respectively. Of the 6 SOT recipients with positive B19V polymerase chain reaction, 3 (50%) were admitted to hospital and 2 (33%) were treated with intravenous immunoglobulin. Thus, routine monitoring of B19V in seronegative SOT recipients may not be necessary. Targeted screening 1 month posttransplantation and screening upon clinical suspicion could be an alternative strategy.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transplante de Órgãos / Parvovirus B19 Humano / Hospedeiro Imunocomprometido / Infecções por Parvoviridae Tipo de estudo: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: J Infect Dis Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Dinamarca

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transplante de Órgãos / Parvovirus B19 Humano / Hospedeiro Imunocomprometido / Infecções por Parvoviridae Tipo de estudo: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: J Infect Dis Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Dinamarca