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Generation of HBsAg-reactive T- and B-cells following HBV vaccination in serological non-responders under hemodialysis treatment.
Roch, Toralf; Giesecke-Thiel, Claudia; Blazquez-Navarro, Arturo; Wehler, Patrizia; Thieme, Constantin J; Juelke, Kerstin; Grütz, Gerald; Hörstrup, Jan; Witzke, Oliver; Dittmer, Ulf; Stervbo, Ulrik; Reinke, Petra; Westhoff, Timm H; Babel, Nina.
Afiliação
  • Roch T; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin-Brandenburg Center for Regenerative Therapies, Berlin, Germany.
  • Giesecke-Thiel C; Center for Translational Medicine, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany.
  • Blazquez-Navarro A; Max Planck Institute for Molecular Genetics, Berlin, Germany.
  • Wehler P; Deutsches Rheuma-Forschungszentrum (DRFZ), Berlin, Germany.
  • Thieme CJ; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin-Brandenburg Center for Regenerative Therapies, Berlin, Germany.
  • Juelke K; Center for Translational Medicine, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany.
  • Grütz G; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin-Brandenburg Center for Regenerative Therapies, Berlin, Germany.
  • Hörstrup J; Center for Translational Medicine, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany.
  • Witzke O; Center for Translational Medicine, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany.
  • Dittmer U; BIH Center for Regenerative Therapies (BCRT) Charité - Universitätsmedizin Berlin Inst. f. Med. Immunologie Immunologisches Studienlabor (ISL) - Biomarker, Germany.
  • Stervbo U; BIH Center for Regenerative Therapies (BCRT) Charité - Universitätsmedizin Berlin Inst. f. Med. Immunologie Immunologisches Studienlabor (ISL) - Biomarker, Germany.
  • Reinke P; KfH Nierenzentrum Berlin-Charlottenburg, Berlin, Germany.
  • Westhoff TH; Department of Infectious Diseases, West German Centre of Infectious Diseases, University Hospital Essen, University Duisburg-Essen, Germany.
  • Babel N; Institute for Virology, Universitätsklinikum of University Duisburg-Essen, Essen, Germany.
Eur J Immunol ; 51(5): 1278-1281, 2021 05.
Article em En | MEDLINE | ID: mdl-33459347
ABSTRACT
HBV vaccination is recommend for hemodialysis patients, but only 50-60% of the patients show seroconversion. HBV vaccine-induced generation of HBV reactive T and B cells could be detected regardless of their capacity to mount a serological response, indicating that patients without seroconversion are potentially protected by their HBV-reactive T cell pool.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos B / Ativação Linfocitária / Linfócitos T / Vírus da Hepatite B / Antígenos de Superfície da Hepatite B Limite: Humans Idioma: En Revista: Eur J Immunol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos B / Ativação Linfocitária / Linfócitos T / Vírus da Hepatite B / Antígenos de Superfície da Hepatite B Limite: Humans Idioma: En Revista: Eur J Immunol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Alemanha