Conserved paradoxical relationships among the evolutionary, structural and expressional features of KRAB zinc-finger proteins reveal their special functional characteristics.

Shen, Pan; Xu, Aishi; Hou, Yushan; Wang, Huqiang; Gao, Chao; He, Fuchu; Yang, Dong

Shen, Pan; Xu, Aishi; Hou, Yushan; Wang, Huqiang; Gao, Chao; He, Fuchu; Yang, Dong.

Afiliação

Shen P; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, 102206, China.
Xu A; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, 102206, China.
Hou Y; Animal Sciences College of Jilin University, Changchun, 130062, China.
Wang H; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, 102206, China.
Gao C; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, 102206, China.
He F; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, 102206, China.
Yang D; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, 102206, China. hefc@nic.bmi.ac.cn.

BMC Mol Cell Biol ; 22(1): 7, 2021 Jan 22.

Article em En | MEDLINE | ID: mdl-33482715

Assuntos

Evolução Molecular; Regulação da Expressão Gênica; Proteínas Repressoras/química; Proteínas Repressoras/genética; Dedos de Zinco; Animais; Mamíferos/genética; Filogenia; Domínios Proteicos; Proteínas Repressoras/metabolismo

Palavras-chave

Evolutionary age; Expression; Function; KZFP; Structure

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Regulação da Expressão Gênica / Dedos de Zinco / Evolução Molecular Limite: Animals Idioma: En Revista: BMC Mol Cell Biol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China

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