Overexpression of secretory leukocyte peptidase inhibitor (SLPI) does not modulate experimental osteoarthritis but may be a biomarker for the disease.

Kim, H-E; Shin, Y; Jung, I J; Yang, J-I; Chun, C-H; Kim, H A; Chun, J-S

Kim, H-E; Shin, Y; Jung, I J; Yang, J-I; Chun, C-H; Kim, H A; Chun, J-S.

Afiliação

Kim HE; National Creative Research Initiatives Center for Osteoarthritis Pathogenesis and School of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, 61005, Republic of Korea.
Shin Y; National Creative Research Initiatives Center for Osteoarthritis Pathogenesis and School of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, 61005, Republic of Korea.
Jung IJ; National Creative Research Initiatives Center for Osteoarthritis Pathogenesis and School of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, 61005, Republic of Korea.
Yang JI; National Creative Research Initiatives Center for Osteoarthritis Pathogenesis and School of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, 61005, Republic of Korea.
Chun CH; Department of Orthopedic Surgery, Wonkwang University School of Medicine, Iksan, 54538, Republic of Korea.
Kim HA; Department of Internal Medicine, Hallym University, Sacred Heart Hospital, Anyang, 14068, Republic of Korea.
Chun JS; National Creative Research Initiatives Center for Osteoarthritis Pathogenesis and School of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, 61005, Republic of Korea. Electronic address: jschun@gist.ac.kr.

Osteoarthritis Cartilage ; 29(4): 558-567, 2021 04.

Article em En | MEDLINE | ID: mdl-33485930

Assuntos

Artrite Experimental/genética; Fatores de Transcrição Hélice-Alça-Hélice Básicos/genética; Condrócitos/metabolismo; Osteoartrite do Joelho/genética; Inibidor Secretado de Peptidases Leucocitárias/genética; Inibidor Secretado de Peptidases Leucocitárias/metabolismo; Animais; Artrite Experimental/metabolismo; Cartilagem Articular; Humanos; Meniscos Tibiais/cirurgia; Camundongos; Osteoartrite/genética; Osteoartrite/metabolismo; Osteoartrite do Joelho/metabolismo; Cultura Primária de Células; Reação em Cadeia da Polimerase Via Transcriptase Reversa; Sinoviócitos

Palavras-chave

Biomarker; Chondrocytes; Microarray; Osteoarthritis; Secretory leukocyte peptidase inhibitor (SLPI)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Artrite Experimental / Condrócitos / Osteoartrite do Joelho / Fatores de Transcrição Hélice-Alça-Hélice Básicos / Inibidor Secretado de Peptidases Leucocitárias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Osteoarthritis Cartilage Assunto da revista: ORTOPEDIA / REUMATOLOGIA Ano de publicação: 2021 Tipo de documento: Article

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