LncRNA CBR3-AS1 regulates of breast cancer drug sensitivity as a competing endogenous RNA through the JNK1/MEK4-mediated MAPK signal pathway.

Zhang, Ming; Wang, Yan; Jiang, Longyang; Song, Xinyue; Zheng, Ang; Gao, Hua; Wei, Minjie; Zhao, Lin

Zhang, Ming; Wang, Yan; Jiang, Longyang; Song, Xinyue; Zheng, Ang; Gao, Hua; Wei, Minjie; Zhao, Lin.

Afiliação

Zhang M; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, 110122, Liaoning Province, China.
Wang Y; Liaoning Key Laboratory of molecular targeted anti-tumor drug development and evaluation; Liaoning Cancer immune peptide drug Engineering Technology Research Center; Key Laboratory of Precision Diagnosis and Treatment of Gastrointestinal Tumors, Ministry of Education; China Medical University, Sheny
Jiang L; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, 110122, Liaoning Province, China.
Song X; Liaoning Key Laboratory of molecular targeted anti-tumor drug development and evaluation; Liaoning Cancer immune peptide drug Engineering Technology Research Center; Key Laboratory of Precision Diagnosis and Treatment of Gastrointestinal Tumors, Ministry of Education; China Medical University, Sheny
Zheng A; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, 110122, Liaoning Province, China.
Gao H; Liaoning Key Laboratory of molecular targeted anti-tumor drug development and evaluation; Liaoning Cancer immune peptide drug Engineering Technology Research Center; Key Laboratory of Precision Diagnosis and Treatment of Gastrointestinal Tumors, Ministry of Education; China Medical University, Sheny
Wei M; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, 110122, Liaoning Province, China.
Zhao L; Liaoning Key Laboratory of molecular targeted anti-tumor drug development and evaluation; Liaoning Cancer immune peptide drug Engineering Technology Research Center; Key Laboratory of Precision Diagnosis and Treatment of Gastrointestinal Tumors, Ministry of Education; China Medical University, Sheny

J Exp Clin Cancer Res ; 40(1): 41, 2021 Jan 25.

Article em En | MEDLINE | ID: mdl-33494806

Assuntos

Oxirredutases do Álcool/genética; Neoplasias da Mama/genética; Neoplasias da Mama/metabolismo; MAP Quinase Quinase 4/metabolismo; Sistema de Sinalização das MAP Quinases; Proteína Quinase 8 Ativada por Mitógeno/metabolismo; RNA Longo não Codificante/genética; Adulto; Idoso; Animais; Biomarcadores Tumorais; Neoplasias da Mama/mortalidade; Neoplasias da Mama/patologia; Linhagem Celular Tumoral; Movimento Celular; Proliferação de Células; Modelos Animais de Doenças; Resistencia a Medicamentos Antineoplásicos/genética; Feminino; Perfilação da Expressão Gênica; Humanos; Imuno-Histoquímica; Camundongos; MicroRNAs/genética; Pessoa de Meia-Idade; Modelos Biológicos; Estadiamento de Neoplasias; Prognóstico; Ensaios Antitumorais Modelo de Xenoenxerto

Palavras-chave

Breast cancer; CBR3-AS1; Chemoresistance; MAPK signaling pathway; miR-25-3p

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Sistema de Sinalização das MAP Quinases / MAP Quinase Quinase 4 / Proteína Quinase 8 Ativada por Mitógeno / Oxirredutases do Álcool / RNA Longo não Codificante Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Adult / Aged / Animals / Female / Humans / Middle aged Idioma: En Revista: J Exp Clin Cancer Res Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China

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