COVID-19 Infection in the Human Reproductive Tract of Men and Nonpregnant Women.
Am J Trop Med Hyg
; 104(3): 814-825, 2021 Jan 18.
Article
em En
| MEDLINE
| ID: mdl-33534765
ABSTRACT
SARS-CoV-2 is an enveloped non-segmented positive-sense RNA virus, classified as a beta coronavirus, responsible for the COVID-19 pandemic. Angiotensin-converting enzyme 2 (ACE2), reported as a SARS-CoV-2 receptor, is expressed in different human tissues (lung, intestine, and kidney) and in the testis, ovaries, uterus, and vagina. This suggests a potential risk to the human reproductive tract in COVID-19 patients. In addition, SARS-CoV-2 RNA has been detected in the blood, urine, facial/anal swabs, semen, and vaginal secretion, suggesting other potential means of transmission. However, little has been reported about SARS-CoV-2 infection in the male and nonpregnant female reproductive tracts, which may provide direct evidence on sexual transmission and fertility problems. Therefore, we focused this narrative review mainly on the distribution of ACE2 and SARS-CoV-2 positivity in the male and nonpregnant female reproductive tracts, providing an overview of the potential threat of COVID-19 to reproductive health and sexual transmission.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
SARS-CoV-2
/
COVID-19
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Genitália Feminina
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Genitália Masculina
Limite:
Female
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Humans
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Male
/
Pregnancy
Idioma:
En
Revista:
Am J Trop Med Hyg
Ano de publicação:
2021
Tipo de documento:
Article