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Synthesis of novel 3/5(3,5)-(di)nitropaeonol hydrazone derivatives as nematicidal agents.
Chen, Gen-Qiang; Zhu, Li-Na; Yang, Jin-Ming; Zhang, Song; Li, Yuan-Hao; Guo, Xiao-Long; Sun, Di; He, Jia-Xuan; Tian, Yue-E; Liu, Sheng-Ming; Jiang, Jia; Huang, Xiao-Bo; Che, Zhi-Ping.
Afiliação
  • Chen GQ; Laboratory of Pesticidal Design & Synthesis, Department of Plant Protection, College of Forestry, Henan University of Science and Technology, Luoyang 471023, China.
  • Zhu LN; Laboratory of Pesticidal Design & Synthesis, Department of Plant Protection, College of Forestry, Henan University of Science and Technology, Luoyang 471023, China.
  • Yang JM; Laboratory of Pesticidal Design & Synthesis, Department of Plant Protection, College of Forestry, Henan University of Science and Technology, Luoyang 471023, China.
  • Zhang S; Laboratory of Pesticidal Design & Synthesis, Department of Plant Protection, College of Forestry, Henan University of Science and Technology, Luoyang 471023, China.
  • Li YH; Laboratory of Pesticidal Design & Synthesis, Department of Plant Protection, College of Forestry, Henan University of Science and Technology, Luoyang 471023, China.
  • Guo XL; Laboratory of Pesticidal Design & Synthesis, Department of Plant Protection, College of Forestry, Henan University of Science and Technology, Luoyang 471023, China.
  • Sun D; Laboratory of Pesticidal Design & Synthesis, Department of Plant Protection, College of Forestry, Henan University of Science and Technology, Luoyang 471023, China.
  • He JX; Laboratory of Pesticidal Design & Synthesis, Department of Plant Protection, College of Forestry, Henan University of Science and Technology, Luoyang 471023, China.
  • Tian YE; Laboratory of Pesticidal Design & Synthesis, Department of Plant Protection, College of Forestry, Henan University of Science and Technology, Luoyang 471023, China.
  • Liu SM; Laboratory of Pesticidal Design & Synthesis, Department of Plant Protection, College of Forestry, Henan University of Science and Technology, Luoyang 471023, China.
  • Jiang J; Laboratory of Pesticidal Design & Synthesis, Department of Plant Protection, College of Forestry, Henan University of Science and Technology, Luoyang 471023, China.
  • Huang XB; Laboratory of Pesticidal Design & Synthesis, Department of Plant Protection, College of Forestry, Henan University of Science and Technology, Luoyang 471023, China.
  • Che ZP; Laboratory of Pesticidal Design & Synthesis, Department of Plant Protection, College of Forestry, Henan University of Science and Technology, Luoyang 471023, China.
J Asian Nat Prod Res ; 24(1): 66-75, 2022 Jan.
Article em En | MEDLINE | ID: mdl-33550877
ABSTRACT
Eighteen novel 3/5(3,5)-(di)nitropaeonol hydrazone derivatives were prepared, and their structures well characterized by 1H NMR, HRMS, and mp. Due to the steric hindrance, the substituents on the C = N double bond of all hydrazine compounds (except E/Z = 4/1 for IV-1g, IV-1l, IV-2b, and E/Z = 3/2 for IV-1n, IV-3a) adopted E configuration. Among all compounds, four compounds 2, 4, IV-1j, and IV-1n exhibited potent nematicidal activity than their precursor paeonol, especially 5-nitropaeonol (2) and 3,5-dinitropaeonol (4) displayed the most potent nematicidal activity Heterodera glycines in vivo with LC50 values of 32.3307 and 36.7074 mg/L, respectively.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tylenchoidea / Hidrazonas Limite: Animals Idioma: En Revista: J Asian Nat Prod Res Assunto da revista: BOTANICA / QUIMICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tylenchoidea / Hidrazonas Limite: Animals Idioma: En Revista: J Asian Nat Prod Res Assunto da revista: BOTANICA / QUIMICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China