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Phage Biobank: Present Challenges and Future Perspectives.
Lin, Ruby Cy; Sacher, Jessica C; Ceyssens, Pieter-Jan; Zheng, Jan; Khalid, Ali; Iredell, Jonathan R.
Afiliação
  • Lin RC; Centre for Infectious Diseases and Microbiology, Westmead Institute for Medical Research, Sydney, Australia; Faculty of Medicine and Health, School of Medical Sciences, The University of Sydney, Sydney, Australia; School of Medical Sciences, University of New South Wales, Sydney, Australia. Electron
  • Sacher JC; Phage Directory, Atlanta, Georgia, USA. Electronic address: jessica@phage.directory.
  • Ceyssens PJ; Antibiotics and Resistance Unit, The National Reference Centres for Salmonella, Shigella, Listeria, Neisseria and Mycobacteria, Sciensano, Belgium.
  • Zheng J; Phage Directory, Atlanta, Georgia, USA. Electronic address: jan@phage.directory.
  • Khalid A; Centre for Infectious Diseases and Microbiology, Westmead Institute for Medical Research, Sydney, Australia; Faculty of Medicine and Health, School of Medical Sciences, The University of Sydney, Sydney, Australia.
  • Iredell JR; Centre for Infectious Diseases and Microbiology, Westmead Institute for Medical Research, Sydney, Australia; Faculty of Medicine and Health, School of Medical Sciences, The University of Sydney, Sydney, Australia; Westmead Hospital, Western Sydney Local Health District, Sydney, Australia. Electronic
Curr Opin Biotechnol ; 68: 221-230, 2021 04.
Article em En | MEDLINE | ID: mdl-33581425
After a century of use in human infection, the preparation and administration of therapeutic bacteriophages (phages) still relies on ad hoc partnerships of researchers, biotech companies, clinicians and regulators. There is a clear need to improve the reproducibility, safety and speed of the provision of suitable phages. Here we discuss the specific characteristics and challenges of a sustainable phage biobank and, as we build a national consortium aimed at delivering phage therapeutics, suggest a roadmap toward national biobanking and phage therapy initiatives using the Australian context as a model.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bacteriófagos / Terapia por Fagos Tipo de estudo: Prognostic_studies Limite: Humans País/Região como assunto: Oceania Idioma: En Revista: Curr Opin Biotechnol Assunto da revista: BIOTECNOLOGIA Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bacteriófagos / Terapia por Fagos Tipo de estudo: Prognostic_studies Limite: Humans País/Região como assunto: Oceania Idioma: En Revista: Curr Opin Biotechnol Assunto da revista: BIOTECNOLOGIA Ano de publicação: 2021 Tipo de documento: Article