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Targeting EphA2 suppresses hepatocellular carcinoma initiation and progression by dual inhibition of JAK1/STAT3 and AKT signaling.
Wang, Hao; Hou, Wei; Perera, Aldeb; Bettler, Carlee; Beach, Jordan R; Ding, Xianzhong; Li, Jun; Denning, Mitchell F; Dhanarajan, Asha; Cotler, Scott J; Joyce, Cara; Yin, Jun; Ahmed, Fowsiyo; Roberts, Lewis R; Qiu, Wei.
Afiliação
  • Wang H; Department of Surgery, Loyola University Chicago Stritch School of Medicine, Maywood, IL, USA; Department of Cancer Biology, Loyola University Chicago Stritch School of Medicine, Maywood, IL, USA.
  • Hou W; Department of Surgery, Loyola University Chicago Stritch School of Medicine, Maywood, IL, USA; Department of Cancer Biology, Loyola University Chicago Stritch School of Medicine, Maywood, IL, USA.
  • Perera A; Department of Surgery, Loyola University Chicago Stritch School of Medicine, Maywood, IL, USA; Department of Cancer Biology, Loyola University Chicago Stritch School of Medicine, Maywood, IL, USA.
  • Bettler C; Department of Surgery, Loyola University Chicago Stritch School of Medicine, Maywood, IL, USA; Department of Cancer Biology, Loyola University Chicago Stritch School of Medicine, Maywood, IL, USA.
  • Beach JR; Department of Cell and Molecular Physiology, Loyola University Chicago Stritch School of Medicine, Maywood, IL, USA.
  • Ding X; Department of Pathology, Loyola University Chicago Stritch School of Medicine, Maywood, IL, USA.
  • Li J; Department of Applied and Computational Mathematics and Statistics, University of Notre Dame, Notre Dame, IN, USA.
  • Denning MF; Department of Cancer Biology, Loyola University Chicago Stritch School of Medicine, Maywood, IL, USA.
  • Dhanarajan A; Department of Medicine, Loyola University Chicago Stritch School of Medicine, Maywood, IL, USA.
  • Cotler SJ; Department of Medicine, Loyola University Chicago Stritch School of Medicine, Maywood, IL, USA.
  • Joyce C; Department of Public Health Sciences, Loyola University Chicago Stritch School of Medicine, Maywood, IL, USA.
  • Yin J; Department of Medicine, Mayo Clinic, Rochester, MN, USA.
  • Ahmed F; Department of Medicine, Mayo Clinic, Rochester, MN, USA.
  • Roberts LR; Department of Medicine, Mayo Clinic, Rochester, MN, USA.
  • Qiu W; Department of Surgery, Loyola University Chicago Stritch School of Medicine, Maywood, IL, USA; Department of Cancer Biology, Loyola University Chicago Stritch School of Medicine, Maywood, IL, USA. Electronic address: wqiu@luc.edu.
Cell Rep ; 34(8): 108765, 2021 02 23.
Article em En | MEDLINE | ID: mdl-33626345
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Benzamidas / Niacinamida / Carcinoma Hepatocelular / Receptor EphA2 / Proteínas Proto-Oncogênicas c-akt / Fator de Transcrição STAT3 / Janus Quinase 1 / Neoplasias Hepáticas / Antineoplásicos Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Cell Rep Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Benzamidas / Niacinamida / Carcinoma Hepatocelular / Receptor EphA2 / Proteínas Proto-Oncogênicas c-akt / Fator de Transcrição STAT3 / Janus Quinase 1 / Neoplasias Hepáticas / Antineoplásicos Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Cell Rep Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos