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Fc galactosylation follows consecutive reaction kinetics and enhances immunoglobulin G hexamerization for complement activation.
Wei, Bingchuan; Gao, Xuan; Cadang, Lance; Izadi, Saeed; Liu, Peilu; Zhang, Hui-Min; Hecht, Elizabeth; Shim, Jeongsup; Magill, Gordon; Pabon, Juan Rincon; Dai, Lu; Phung, Wilson; Lin, Elaine; Wang, Christopher; Whang, Kevin; Sanchez, Sean; Oropeza, Jose; Camperi, Julien; Zhang, Jennifer; Sandoval, Wendy; Zhang, Yonghua Taylor; Jiang, Guoying.
Afiliação
  • Wei B; Protein Analytical Chemistry, Genentech Inc., South San Francisco,United States.
  • Gao X; Small Molecule Analytical Chemistry, Genentech Inc, South San Francisco, United States.
  • Cadang L; Biological Technologies, Genentech Inc., South San Francisco, United States.
  • Izadi S; Protein Analytical Chemistry, Genentech Inc., South San Francisco,United States.
  • Liu P; Pharmaceutical Development, Genentech Inc., South San Francisco, United States.
  • Zhang HM; Protein Analytical Chemistry, Genentech Inc., South San Francisco,United States.
  • Hecht E; Department of Chemistry and Biochemistry, Florida State University,Florida, United States.
  • Shim J; Protein Analytical Chemistry, Genentech Inc., South San Francisco,United States.
  • Magill G; Department of Microchemistry, Proteomics and Lipidomics, Genentech Inc., South San Francisco, United States.
  • Pabon JR; Biological Technologies, Genentech Inc., South San Francisco, United States.
  • Dai L; Department of Cell Culture and Bioprocess Operations, Genentech Inc., South San Francisco, United States.
  • Phung W; Protein Analytical Chemistry, Genentech Inc., South San Francisco,United States.
  • Lin E; Department of Chemistry, University of Kansas, Lawrence United States.
  • Wang C; Protein Analytical Chemistry, Genentech Inc., South San Francisco,United States.
  • Whang K; Department of Microchemistry, Proteomics and Lipidomics, Genentech Inc., South San Francisco, United States.
  • Sanchez S; Biological Technologies, Genentech Inc., South San Francisco, United States.
  • Oropeza J; Biological Technologies, Genentech Inc., South San Francisco, United States.
  • Camperi J; Biological Technologies, Genentech Inc., South San Francisco, United States.
  • Zhang J; Biological Technologies, Genentech Inc., South San Francisco, United States.
  • Sandoval W; Biological Technologies, Genentech Inc., South San Francisco, United States.
  • Zhang YT; Protein Analytical Chemistry, Genentech Inc., South San Francisco,United States.
  • Jiang G; Protein Analytical Chemistry, Genentech Inc., South San Francisco,United States.
MAbs ; 13(1): 1893427, 2021.
Article em En | MEDLINE | ID: mdl-33682619
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Imunoglobulina G / Fragmentos Fc das Imunoglobulinas / Complemento C1q / Processamento de Proteína Pós-Traducional / Ativação do Complemento / Citotoxicidade Imunológica / Galactose / Anticorpos Monoclonais Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: MAbs Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Imunoglobulina G / Fragmentos Fc das Imunoglobulinas / Complemento C1q / Processamento de Proteína Pós-Traducional / Ativação do Complemento / Citotoxicidade Imunológica / Galactose / Anticorpos Monoclonais Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: MAbs Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos