IL-17 deficiency aggravates the streptozotocin-induced diabetic nephropathy through the reduction of autophagosome formation in mice.

Kim, Kyung-Hyun; Hong, Geum-Lan; Jung, Da-Young; Karunasagara, Shanika; Jeong, Won-Il; Jung, Ju-Young

Kim, Kyung-Hyun; Hong, Geum-Lan; Jung, Da-Young; Karunasagara, Shanika; Jeong, Won-Il; Jung, Ju-Young.

Afiliação

Kim KH; Department of Veterinary Medicine, Institute of Veterinary Science, Chungnam National University, 99, Daehak-ro, Yuseong-gu, Daejeon, 34134, Republic of Korea.
Hong GL; Department of Veterinary Medicine, Institute of Veterinary Science, Chungnam National University, 99, Daehak-ro, Yuseong-gu, Daejeon, 34134, Republic of Korea.
Jung DY; Department of Veterinary Medicine, Institute of Veterinary Science, Chungnam National University, 99, Daehak-ro, Yuseong-gu, Daejeon, 34134, Republic of Korea.
Karunasagara S; Department of Veterinary Medicine, Institute of Veterinary Science, Chungnam National University, 99, Daehak-ro, Yuseong-gu, Daejeon, 34134, Republic of Korea.
Jeong WI; Laboratory of Liver Research, Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, 34141, Republic of Korea.
Jung JY; Department of Veterinary Medicine, Institute of Veterinary Science, Chungnam National University, 99, Daehak-ro, Yuseong-gu, Daejeon, 34134, Republic of Korea. jyjung@cnu.ac.kr.

Mol Med ; 27(1): 25, 2021 03 10.

Article em En | MEDLINE | ID: mdl-33691614

Assuntos

Autofagossomos/imunologia; Citocinas/imunologia; Diabetes Mellitus Experimental/imunologia; Nefropatias Diabéticas/imunologia; Animais; Proteína 7 Relacionada à Autofagia/metabolismo; Proteínas Relacionadas à Autofagia/metabolismo; Linhagem Celular; Citocinas/genética; Diabetes Mellitus Experimental/induzido quimicamente; Diabetes Mellitus Experimental/metabolismo; Diabetes Mellitus Experimental/patologia; Nefropatias Diabéticas/induzido quimicamente; Nefropatias Diabéticas/patologia; Humanos; Rim/imunologia; Rim/metabolismo; Rim/patologia; Masculino; Camundongos Endogâmicos C57BL; Camundongos Knockout; Proteínas Associadas aos Microtúbulos/metabolismo; Fator de Transcrição STAT3/metabolismo; Estreptozocina; Enzimas de Conjugação de Ubiquitina/metabolismo

Palavras-chave

Autophagosome formation; Autophagy; Diabetic nephropathy; IL-17A

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Citocinas / Diabetes Mellitus Experimental / Nefropatias Diabéticas / Autofagossomos Limite: Animals / Humans / Male Idioma: En Revista: Mol Med Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2021 Tipo de documento: Article

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