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In a mouse model of INCL reduced S-palmitoylation of cytosolic thioesterase APT1 contributes to microglia proliferation and neuroinflammation.
Sadhukhan, Tamal; Bagh, Maria B; Appu, Abhilash P; Mondal, Avisek; Zhang, Wei; Liu, Aiyi; Mukherjee, Anil B.
Afiliação
  • Sadhukhan T; Section on Developmental Genetics, Division of Translational Medicine, Eunice Kennedy Shriver National Institute of Child Health and Human Development, The National Institutes of Health, Bethesda, Maryland, USA.
  • Bagh MB; Section on Developmental Genetics, Division of Translational Medicine, Eunice Kennedy Shriver National Institute of Child Health and Human Development, The National Institutes of Health, Bethesda, Maryland, USA.
  • Appu AP; Section on Developmental Genetics, Division of Translational Medicine, Eunice Kennedy Shriver National Institute of Child Health and Human Development, The National Institutes of Health, Bethesda, Maryland, USA.
  • Mondal A; Section on Developmental Genetics, Division of Translational Medicine, Eunice Kennedy Shriver National Institute of Child Health and Human Development, The National Institutes of Health, Bethesda, Maryland, USA.
  • Zhang W; Biostatistics and Bioinformatics Branch (HNT72), Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, Maryland, USA.
  • Liu A; Biostatistics and Bioinformatics Branch (HNT72), Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, Maryland, USA.
  • Mukherjee AB; Section on Developmental Genetics, Division of Translational Medicine, Eunice Kennedy Shriver National Institute of Child Health and Human Development, The National Institutes of Health, Bethesda, Maryland, USA.
J Inherit Metab Dis ; 44(4): 1051-1069, 2021 07.
Article em En | MEDLINE | ID: mdl-33739454
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tioléster Hidrolases / Lipofuscinoses Ceroides Neuronais Limite: Animals / Female / Humans / Male Idioma: En Revista: J Inherit Metab Dis Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tioléster Hidrolases / Lipofuscinoses Ceroides Neuronais Limite: Animals / Female / Humans / Male Idioma: En Revista: J Inherit Metab Dis Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos