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MEK inhibition preferentially suppresses anchorage-independent growth in osteosarcoma cells and decreases tumors in vivo.
Shimizu, Takatsune; Kimura, Kiyomi; Sugihara, Eiji; Yamaguchi-Iwai, Sayaka; Nobusue, Hiroyuki; Sampetrean, Oltea; Otsuki, Yuji; Fukuchi, Yumi; Saitoh, Kaori; Kato, Keiko; Soga, Tomoyoshi; Muto, Akihiro; Saya, Hideyuki.
Afiliação
  • Shimizu T; Department of Pathophysiology, School of Pharmacy and Pharmaceutical Sciences, Hoshi University, Shinagawa-ku, Tokyo, Japan.
  • Kimura K; Division of Gene Regulation, Institute for Advanced Medical Research, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.
  • Sugihara E; Department of Pathophysiology, School of Pharmacy and Pharmaceutical Sciences, Hoshi University, Shinagawa-ku, Tokyo, Japan.
  • Yamaguchi-Iwai S; Division of Gene Regulation, Institute for Advanced Medical Research, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.
  • Nobusue H; Division of Gene Regulation, Institute for Advanced Medical Research, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.
  • Sampetrean O; Research and Development Center for Precision Medicine, University of Tsukuba, Ibaraki, Japan.
  • Otsuki Y; Department of Pathophysiology, School of Pharmacy and Pharmaceutical Sciences, Hoshi University, Shinagawa-ku, Tokyo, Japan.
  • Fukuchi Y; Department of Orthopedic Surgery, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.
  • Saitoh K; Division of Gene Regulation, Institute for Advanced Medical Research, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.
  • Kato K; Division of Gene Regulation, Institute for Advanced Medical Research, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.
  • Soga T; Division of Gene Regulation, Institute for Advanced Medical Research, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.
  • Muto A; Department of Pathophysiology, School of Pharmacy and Pharmaceutical Sciences, Hoshi University, Shinagawa-ku, Tokyo, Japan.
  • Saya H; Institute for Advanced Biosciences, Keio University, Tsuruoka, Japan.
J Orthop Res ; 39(12): 2732-2743, 2021 12.
Article em En | MEDLINE | ID: mdl-33751653
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ósseas / Osteossarcoma Limite: Animals Idioma: En Revista: J Orthop Res Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Japão
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ósseas / Osteossarcoma Limite: Animals Idioma: En Revista: J Orthop Res Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Japão