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Insertion of metal carbenes into the anilinic N-H bond of unprotected aminobenzenesulfonamides delivers low nanomolar inhibitors of human carbonic anhydrase IX and XII isoforms.
Sharonova, Tatiana; Paramonova, Polina; Kalinin, Stanislav; Bunev, Alexander; Gasanov, Rovshan Е; Nocentini, Alessio; Sharoyko, Vladimir; Tennikova, Tatiana B; Dar'in, Dmitry; Supuran, Claudiu T; Krasavin, Mikhail.
Afiliação
  • Sharonova T; Saint Petersburg State University, Saint Petersburg, 199034, Russian Federation.
  • Paramonova P; Saint Petersburg State University, Saint Petersburg, 199034, Russian Federation.
  • Kalinin S; Saint Petersburg State University, Saint Petersburg, 199034, Russian Federation.
  • Bunev A; Medicinal Chemistry Center, Togliatti State University, Togliatti, 445020, Russian Federation.
  • Gasanov RЕ; Medicinal Chemistry Center, Togliatti State University, Togliatti, 445020, Russian Federation.
  • Nocentini A; Neurofarba Department, Universita degli Studi di Firenze, Florence, 50019, Italy.
  • Sharoyko V; Saint Petersburg State University, Saint Petersburg, 199034, Russian Federation.
  • Tennikova TB; Saint Petersburg State University, Saint Petersburg, 199034, Russian Federation.
  • Dar'in D; Saint Petersburg State University, Saint Petersburg, 199034, Russian Federation.
  • Supuran CT; Neurofarba Department, Universita degli Studi di Firenze, Florence, 50019, Italy. Electronic address: claudiu.supuran@unifi.it.
  • Krasavin M; Saint Petersburg State University, Saint Petersburg, 199034, Russian Federation. Electronic address: m.krasavin@spbu.ru.
Eur J Med Chem ; 218: 113352, 2021 Jun 05.
Article em En | MEDLINE | ID: mdl-33774343
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfonamidas / Inibidores da Anidrase Carbônica / Complexos de Coordenação / Aminobenzoatos / Metano / Antineoplásicos Limite: Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfonamidas / Inibidores da Anidrase Carbônica / Complexos de Coordenação / Aminobenzoatos / Metano / Antineoplásicos Limite: Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2021 Tipo de documento: Article