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Genome-wide association study of fleece traits in Inner Mongolia Cashmere goats.
Wang, F H; Zhang, L; Gong, G; Yan, X C; Zhang, L T; Zhang, F T; Liu, H F; Lv, Q; Wang, Z Y; Wang, R J; Zhang, Y J; Wang, Z X; Liu, Z H; He, L B; Su, R; Zhao, Y H; Li, J Q.
Afiliação
  • Wang FH; College of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.
  • Zhang L; College of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.
  • Gong G; College of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.
  • Yan XC; College of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.
  • Zhang LT; College of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.
  • Zhang FT; College of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.
  • Liu HF; College of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.
  • Lv Q; College of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.
  • Wang ZY; College of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.
  • Wang RJ; College of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.
  • Zhang YJ; College of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.
  • Wang ZX; College of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.
  • Liu ZH; Key Laboratory of Animal Genetics, Breeding and Reproduction, Hohhot, Inner Mongolia Autonomous Region, 010018, China.
  • He LB; College of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.
  • Su R; Key Laboratory of Mutton Sheep Genetics and Breeding, Ministry of Agriculture and Rural Affairs, Hohhot, 010018, China.
  • Zhao YH; Key Laboratory of Mutton Sheep Genetics and Breeding, Ministry of Agriculture and Rural Affairs, Hohhot, 010018, China.
  • Li JQ; College of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.
Anim Genet ; 52(3): 375-379, 2021 Jun.
Article em En | MEDLINE | ID: mdl-33778967
ABSTRACT
Inner Mongolia Cashmere goat is a well-known local cashmere goat breed in China. It is famous for excellent fleece quality and a significant advantage in cashmere yield compared to other cashmere goat breeds. In this study, a genome-wide association study was used to investigate fiber length, fiber diameter, and cashmere yield of 192 Inner Mongolia Cashmere goats using the Illumina GoatSNP52K Beadchip panel. We discovered that four single nucleotide polymorphisms (SNPs) reached genome-wide significance levels. These SNPs were located in some genes, e.g. FGF12, SEMA3D, EVPL, and SOX5, possibly related to fleece traits in Inner Mongolia Cashmere goat. Gene ontology enrichment analysis revealed that these genes were enriched in several biological pathways that were involved in hair follicle development in cashmere goats. In summary, the identified significant SNPs and genes provide useful information to explore genetic mechanisms underlying the variation in fleece traits and genomic selection of Chinese cashmere goat.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cabras / Estudo de Associação Genômica Ampla / Cabelo Tipo de estudo: Risk_factors_studies Limite: Animals País/Região como assunto: Asia Idioma: En Revista: Anim Genet Assunto da revista: GENETICA / MEDICINA VETERINARIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cabras / Estudo de Associação Genômica Ampla / Cabelo Tipo de estudo: Risk_factors_studies Limite: Animals País/Região como assunto: Asia Idioma: En Revista: Anim Genet Assunto da revista: GENETICA / MEDICINA VETERINARIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China