Your browser doesn't support javascript.
loading
Quantifying single-cell ERK dynamics in colorectal cancer organoids reveals EGFR as an amplifier of oncogenic MAPK pathway signalling.
Ponsioen, Bas; Post, Jasmin B; Buissant des Amorie, Julian R; Laskaris, Dimitrios; van Ineveld, Ravian L; Kersten, Simone; Bertotti, Andrea; Sassi, Francesco; Sipieter, François; Cappe, Benjamin; Mertens, Sander; Verlaan-Klink, Ingrid; Boj, Sylvia F; Vries, Rob G J; Rehmann, Holger; Vandenabeele, Peter; Riquet, Franck B; Trusolino, Livio; Bos, Johannes L; Snippert, Hugo J G.
Afiliação
  • Ponsioen B; Molecular Cancer Research, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
  • Post JB; Oncode Institute, Utrecht, Netherlands.
  • Buissant des Amorie JR; Molecular Cancer Research, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
  • Laskaris D; Oncode Institute, Utrecht, Netherlands.
  • van Ineveld RL; Molecular Cancer Research, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
  • Kersten S; Oncode Institute, Utrecht, Netherlands.
  • Bertotti A; Molecular Cancer Research, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
  • Sassi F; Oncode Institute, Utrecht, Netherlands.
  • Sipieter F; Molecular Cancer Research, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
  • Cappe B; Oncode Institute, Utrecht, Netherlands.
  • Mertens S; Molecular Cancer Research, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
  • Verlaan-Klink I; Oncode Institute, Utrecht, Netherlands.
  • Boj SF; Laboratory of Translational Cancer Medicine, Candiolo Cancer Institute - FPO IRCCs, Candiolo, Torino, Italy.
  • Vries RGJ; Department of Oncology, University of Torino School of Medicine, Candiolo, Torino, Italy.
  • Rehmann H; Laboratory of Translational Cancer Medicine, Candiolo Cancer Institute - FPO IRCCs, Candiolo, Torino, Italy.
  • Vandenabeele P; Molecular Signaling and Cell Death Unit, Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
  • Riquet FB; Molecular Signaling and Cell Death Unit, Center for Inflammation Research (IRC), a VIB-UGent department, Ghent, Belgium.
  • Trusolino L; Institut Jacques Monod, CNRS UMR 7592, Université Paris Diderot, Paris, France.
  • Bos JL; Molecular Signaling and Cell Death Unit, Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
  • Snippert HJG; Molecular Signaling and Cell Death Unit, Center for Inflammation Research (IRC), a VIB-UGent department, Ghent, Belgium.
Nat Cell Biol ; 23(4): 377-390, 2021 04.
Article em En | MEDLINE | ID: mdl-33795873
Assuntos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Proteínas Proto-Oncogênicas p21(ras) / Proteínas Proto-Oncogênicas B-raf / Inibidores de Proteínas Quinases Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nat Cell Biol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Holanda
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Proteínas Proto-Oncogênicas p21(ras) / Proteínas Proto-Oncogênicas B-raf / Inibidores de Proteínas Quinases Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nat Cell Biol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Holanda