Intratumoural Cytochrome P450 Expression in Breast Cancer: Impact on Standard of Care Treatment and New Efforts to Develop Tumour-Selective Therapies.

Sneha, Smarakan; Baker, Simon C; Green, Andrew; Storr, Sarah; Aiyappa, Radhika; Martin, Stewart; Pors, Klaus

Sneha, Smarakan; Baker, Simon C; Green, Andrew; Storr, Sarah; Aiyappa, Radhika; Martin, Stewart; Pors, Klaus.

Afiliação

Sneha S; Institute of Cancer Therapeutics, School of Pharmacy and Medical Sciences, Faculty of Life Sciences, University of Bradford, Bradford BD7 1DP, UK.
Baker SC; Jack Birch Unit for Molecular Carcinogenesis, Department of Biology & York Biomedical Research Institute, University of York, Heslington, York YO10 5DD, UK.
Green A; Nottingham Breast Cancer Research Centre, School of Medicine, Biodiscovery Institute, University Park, Nottingham NG7 2RD, UK.
Storr S; Nottingham Breast Cancer Research Centre, School of Medicine, Biodiscovery Institute, University Park, Nottingham NG7 2RD, UK.
Aiyappa R; Nottingham Breast Cancer Research Centre, School of Medicine, Biodiscovery Institute, University Park, Nottingham NG7 2RD, UK.
Martin S; Nottingham Breast Cancer Research Centre, School of Medicine, Biodiscovery Institute, University Park, Nottingham NG7 2RD, UK.
Pors K; Institute of Cancer Therapeutics, School of Pharmacy and Medical Sciences, Faculty of Life Sciences, University of Bradford, Bradford BD7 1DP, UK.

Biomedicines ; 9(3)2021 Mar 12.

Article em En | MEDLINE | ID: mdl-33809117

Palavras-chave

AQ4N; CYP1A1; CYP1B1; CYP2W1; Cytochrome P450; bioprecursor; breast cancer; duocarmycin; phortress; prodrug

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Biomedicines Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido

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