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Small molecule and macrocyclic pyrazole derived inhibitors of myeloperoxidase (MPO).
Hu, Carol H; Neissel Valente, Meriah W; Halpern, O Scott; Jusuf, Sutjano; Khan, Javed A; Locke, Gregory A; Duke, Gerald J; Liu, Xiaoqin; Duclos, Franck J; Wexler, Ruth R; Kick, Ellen K; Smallheer, Joanne M.
Afiliação
  • Hu CH; Research and Development, Bristol-Myers Squibb Company, P. O. Box 5400, Princeton, NJ 08543, United States. Electronic address: carol.hu@bms.com.
  • Neissel Valente MW; Research and Development, Bristol-Myers Squibb Company, P. O. Box 5400, Princeton, NJ 08543, United States. Electronic address: meriah.valente@bms.com.
  • Halpern OS; Research and Development, Bristol-Myers Squibb Company, P. O. Box 5400, Princeton, NJ 08543, United States.
  • Jusuf S; Research and Development, Bristol-Myers Squibb Company, P. O. Box 5400, Princeton, NJ 08543, United States.
  • Khan JA; Research and Development, Bristol-Myers Squibb Company, P. O. Box 5400, Princeton, NJ 08543, United States.
  • Locke GA; Research and Development, Bristol-Myers Squibb Company, P. O. Box 5400, Princeton, NJ 08543, United States.
  • Duke GJ; Research and Development, Bristol-Myers Squibb Company, P. O. Box 5400, Princeton, NJ 08543, United States.
  • Liu X; Research and Development, Bristol-Myers Squibb Company, P. O. Box 5400, Princeton, NJ 08543, United States.
  • Duclos FJ; Research and Development, Bristol-Myers Squibb Company, P. O. Box 5400, Princeton, NJ 08543, United States.
  • Wexler RR; Research and Development, Bristol-Myers Squibb Company, P. O. Box 5400, Princeton, NJ 08543, United States.
  • Kick EK; Research and Development, Bristol-Myers Squibb Company, P. O. Box 5400, Princeton, NJ 08543, United States.
  • Smallheer JM; Research and Development, Bristol-Myers Squibb Company, P. O. Box 5400, Princeton, NJ 08543, United States.
Bioorg Med Chem Lett ; 42: 128010, 2021 06 15.
Article em En | MEDLINE | ID: mdl-33811992
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Peroxidase / Compostos Macrocíclicos / Inibidores Enzimáticos / Bibliotecas de Moléculas Pequenas Limite: Humans Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Peroxidase / Compostos Macrocíclicos / Inibidores Enzimáticos / Bibliotecas de Moléculas Pequenas Limite: Humans Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2021 Tipo de documento: Article