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Gut-inhabiting Clostridia build human GPCR ligands by conjugating neurotransmitters with diet- and human-derived fatty acids.
Chang, Fang-Yuan; Siuti, Piro; Laurent, Stephane; Williams, Thomas; Glassey, Emerson; Sailer, Andreas W; Gordon, David Benjamin; Hemmerle, Horst; Voigt, Christopher A.
Afiliação
  • Chang FY; Synthetic Biology Center, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Siuti P; The Foundry, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Laurent S; Synthetic Biology Group, Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Williams T; Disease Area X, Novartis Institutes for BioMedical Research, Basel, Switzerland.
  • Glassey E; The Foundry, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Sailer AW; Synthetic Biology Center, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Gordon DB; Disease Area X, Novartis Institutes for BioMedical Research, Basel, Switzerland.
  • Hemmerle H; Synthetic Biology Center, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Voigt CA; The Foundry, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Nat Microbiol ; 6(6): 792-805, 2021 06.
Article em En | MEDLINE | ID: mdl-33846627
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neurotransmissores / Ácidos Graxos / Firmicutes / Microbioma Gastrointestinal / Aminas Limite: Humans Idioma: En Revista: Nat Microbiol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neurotransmissores / Ácidos Graxos / Firmicutes / Microbioma Gastrointestinal / Aminas Limite: Humans Idioma: En Revista: Nat Microbiol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos