Influence of vitamin D treatment on functional expression of drug disposition pathways in human kidney proximal tubule cells during simulated uremia.

Tuey, Stacey M; Atilano-Roque, Amandla; Charkoftaki, Georgia; Thurman, Joshua M; Nolin, Thomas D; Joy, Melanie S

Tuey, Stacey M; Atilano-Roque, Amandla; Charkoftaki, Georgia; Thurman, Joshua M; Nolin, Thomas D; Joy, Melanie S.

Afiliação

Tuey SM; Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Aurora, CO, USA.
Atilano-Roque A; Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Aurora, CO, USA.
Charkoftaki G; Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Aurora, CO, USA.
Thurman JM; School of Public Health, Yale University, New Haven, CT, USA.
Nolin TD; Division of Nephrology and Hypertension, School of Medicine, University of Colorado, Aurora, CO, USA.
Joy MS; Department of Pharmacy and Therapeutics, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA, USA.

Xenobiotica ; 51(6): 657-667, 2021 Jun.

Article em En | MEDLINE | ID: mdl-33870862

Assuntos

Transportadores de Ânions Orgânicos; Preparações Farmacêuticas; Uremia; Colecalciferol; Humanos; Rim; Vitamina D

Palavras-chave

CYP enzymes; P-glycoprotein; Renal metabolism; cell culture; organic anion transporter; proximal tubule cells; renal transport; uraemia; vitamin D

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Uremia / Preparações Farmacêuticas / Transportadores de Ânions Orgânicos Limite: Humans Idioma: En Revista: Xenobiotica Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

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