JPT2: The missing link between intracellular Ca2+ release channels and NAADP?
Cell Calcium
; 97: 102405, 2021 Apr 14.
Article
em En
| MEDLINE
| ID: mdl-33873071
ABSTRACT
NAADP (nicotinic acid adenine dinucleotide phosphate) is a potent second messenger releasing Ca2+ from endolysosomes through two-pore channels (TPCs) and from the endoplasmic reticulum (ER) through type 1 ryanodine receptors (RyR1). How NAADP activates these channels, whether directly or indirectly, has been a matter of debate for more than a decade. Now a protein has emerged possibly providing the missing link between TPCs/RyR1 and NAADP.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Cell Calcium
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Alemanha