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Gasdermin D pore structure reveals preferential release of mature interleukin-1.
Xia, Shiyu; Zhang, Zhibin; Magupalli, Venkat Giri; Pablo, Juan Lorenzo; Dong, Ying; Vora, Setu M; Wang, Longfei; Fu, Tian-Min; Jacobson, Matthew P; Greka, Anna; Lieberman, Judy; Ruan, Jianbin; Wu, Hao.
Afiliação
  • Xia S; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.
  • Zhang Z; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
  • Magupalli VG; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.
  • Pablo JL; Department of Pediatrics, Harvard Medical School, Boston, MA, USA.
  • Dong Y; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.
  • Vora SM; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
  • Wang L; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Fu TM; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Jacobson MP; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.
  • Greka A; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
  • Lieberman J; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.
  • Ruan J; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
  • Wu H; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.
Nature ; 593(7860): 607-611, 2021 05.
Article em En | MEDLINE | ID: mdl-33883744
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Ligação a Fosfato / Peptídeos e Proteínas de Sinalização Intracelular / Interleucina-1beta / Inflamassomos / Macrófagos Limite: Animals / Humans Idioma: En Revista: Nature Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Ligação a Fosfato / Peptídeos e Proteínas de Sinalização Intracelular / Interleucina-1beta / Inflamassomos / Macrófagos Limite: Animals / Humans Idioma: En Revista: Nature Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos