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The furin cleavage site in the SARS-CoV-2 spike protein is required for transmission in ferrets.
Peacock, Thomas P; Goldhill, Daniel H; Zhou, Jie; Baillon, Laury; Frise, Rebecca; Swann, Olivia C; Kugathasan, Ruthiran; Penn, Rebecca; Brown, Jonathan C; Sanchez-David, Raul Y; Braga, Luca; Williamson, Maia Kavanagh; Hassard, Jack A; Staller, Ecco; Hanley, Brian; Osborn, Michael; Giacca, Mauro; Davidson, Andrew D; Matthews, David A; Barclay, Wendy S.
Afiliação
  • Peacock TP; Department of Infectious Diseases, Imperial College London, London, UK.
  • Goldhill DH; Department of Infectious Diseases, Imperial College London, London, UK.
  • Zhou J; Department of Infectious Diseases, Imperial College London, London, UK.
  • Baillon L; Department of Infectious Diseases, Imperial College London, London, UK.
  • Frise R; Department of Infectious Diseases, Imperial College London, London, UK.
  • Swann OC; Department of Infectious Diseases, Imperial College London, London, UK.
  • Kugathasan R; Department of Infectious Diseases, Imperial College London, London, UK.
  • Penn R; Department of Infectious Diseases, Imperial College London, London, UK.
  • Brown JC; Department of Infectious Diseases, Imperial College London, London, UK.
  • Sanchez-David RY; Department of Infectious Diseases, Imperial College London, London, UK.
  • Braga L; British Hearth Foundation Centre of Research Excellence, School of Cardiovascular Medicine and Sciences, King's College London, London, UK.
  • Williamson MK; School of Cellular and Molecular Medicine, Faculty of Life Sciences, University of Bristol, Bristol, UK.
  • Hassard JA; Department of Infectious Diseases, Imperial College London, London, UK.
  • Staller E; Department of Infectious Diseases, Imperial College London, London, UK.
  • Hanley B; Department of Cellular Pathology, Northwest London Pathology, Imperial College London NHS Trust, London, UK.
  • Osborn M; Department of Cellular Pathology, Northwest London Pathology, Imperial College London NHS Trust, London, UK.
  • Giacca M; British Hearth Foundation Centre of Research Excellence, School of Cardiovascular Medicine and Sciences, King's College London, London, UK.
  • Davidson AD; School of Cellular and Molecular Medicine, Faculty of Life Sciences, University of Bristol, Bristol, UK.
  • Matthews DA; School of Cellular and Molecular Medicine, Faculty of Life Sciences, University of Bristol, Bristol, UK.
  • Barclay WS; Department of Infectious Diseases, Imperial College London, London, UK. w.barclay@imperial.ac.uk.
Nat Microbiol ; 6(7): 899-909, 2021 07.
Article em En | MEDLINE | ID: mdl-33907312

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Furina / Glicoproteína da Espícula de Coronavírus / SARS-CoV-2 / COVID-19 Limite: Animals / Humans Idioma: En Revista: Nat Microbiol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Furina / Glicoproteína da Espícula de Coronavírus / SARS-CoV-2 / COVID-19 Limite: Animals / Humans Idioma: En Revista: Nat Microbiol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido