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BRAFV600E-induced senescence drives Langerhans cell histiocytosis pathophysiology.
Bigenwald, Camille; Le Berichel, Jessica; Wilk, C Matthias; Chakraborty, Rikhia; Chen, Steven T; Tabachnikova, Alexandra; Mancusi, Rebecca; Abhyankar, Harshal; Casanova-Acebes, Maria; Laface, Ilaria; Akturk, Guray; Jobson, Jenielle; Karoulia, Zoi; Martin, Jerome C; Grout, John; Rafiei, Anahita; Lin, Howard; Manz, Markus G; Baccarini, Alessia; Poulikakos, Poulikos I; Brown, Brian D; Gnjatic, Sacha; Lujambio, Amaia; McClain, Kenneth L; Picarsic, Jennifer; Allen, Carl E; Merad, Miriam.
Afiliação
  • Bigenwald C; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Le Berichel J; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Wilk CM; The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Chakraborty R; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Chen ST; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Tabachnikova A; The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Mancusi R; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Abhyankar H; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Casanova-Acebes M; The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Laface I; Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.
  • Akturk G; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Jobson J; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Karoulia Z; The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Martin JC; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Grout J; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Rafiei A; The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Lin H; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Manz MG; The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Baccarini A; Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.
  • Poulikakos PI; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Brown BD; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Gnjatic S; The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Lujambio A; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • McClain KL; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Picarsic J; The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Allen CE; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Merad M; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Nat Med ; 27(5): 851-861, 2021 05.
Article em En | MEDLINE | ID: mdl-33958797
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células de Langerhans / Histiocitose de Células de Langerhans / Senescência Celular / Proteínas Proto-Oncogênicas B-raf Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Nat Med Assunto da revista: BIOLOGIA MOLECULAR / MEDICINA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células de Langerhans / Histiocitose de Células de Langerhans / Senescência Celular / Proteínas Proto-Oncogênicas B-raf Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Nat Med Assunto da revista: BIOLOGIA MOLECULAR / MEDICINA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos