Paeoniflorin attenuates the allergic contact dermatitis response via inhibiting the IFN-Î³ production and the NF-&#954;B/I&#954;B&#945; signaling pathway in T lymphocytes.

Wu, Xiaoting; Qi, Xiaoyi; Wang, Jing; Zhang, Yunying; Xiao, Yanwei; Tu, Caixia; Wang, Aoxue

Paeoniflorin attenuates the allergic contact dermatitis response via inhibiting the IFN-Î³ production and the NF-κB/IκBα signaling pathway in T lymphocytes.

Wu, Xiaoting; Qi, Xiaoyi; Wang, Jing; Zhang, Yunying; Xiao, Yanwei; Tu, Caixia; Wang, Aoxue.

Afiliação

Wu X; Department of Dermatology, The Second Hospital of Dalian Medical University, Dalian, China; Institute (College) of Integrative Medicine, Dalian Medical University, Dalian, China.
Qi X; Department of Dermatology, Affiliated Hospital of Southwest Medical University, Luzhou, China.
Wang J; Department of Dermatology, The First Affiliated Hospital of Xi'an Medical University, Xi'an, China.
Zhang Y; Department of Dermatology, The Second Hospital of Dalian Medical University, Dalian, China.
Xiao Y; Department of Dermatology, The Second Hospital of Dalian Medical University, Dalian, China.
Tu C; Department of Dermatology, The Second Hospital of Dalian Medical University, Dalian, China; Institute (College) of Integrative Medicine, Dalian Medical University, Dalian, China.
Wang A; Department of Dermatology, The Second Hospital of Dalian Medical University, Dalian, China; Institute (College) of Integrative Medicine, Dalian Medical University, Dalian, China. Electronic address: wangaxdl@163.com.

Int Immunopharmacol ; 96: 107687, 2021 Jul.

Article em En | MEDLINE | ID: mdl-33965879

Assuntos

Dermatite Alérgica de Contato/tratamento farmacológico; Glucosídeos/farmacologia; Inflamação/dietoterapia; Interferon gama/antagonistas & inibidores; Monoterpenos/farmacologia; Inibidor de NF-kappaB alfa/metabolismo; NF-kappa B/metabolismo; Linfócitos T/imunologia; Animais; Anti-Inflamatórios não Esteroides/farmacologia; Células Cultivadas; Dermatite Alérgica de Contato/imunologia; Dermatite Alérgica de Contato/patologia; Modelos Animais de Doenças; Humanos; Inflamação/imunologia; Inflamação/patologia; Inibidor de NF-kappaB alfa/genética; NF-kappa B/genética; Transdução de Sinais; Linfócitos T/efeitos dos fármacos

Palavras-chave

Allergic contact dermatitis; Mice; NF-κB signaling pathway; Paeoniflorin; T lymphocytes

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T / NF-kappa B / Interferon gama / Dermatite Alérgica de Contato / Monoterpenos / Inibidor de NF-kappaB alfa / Glucosídeos / Inflamação Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Int Immunopharmacol Assunto da revista: ALERGIA E IMUNOLOGIA / FARMACOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China

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