The Molecular Mechanism of <i>Scutellaria baicalensis</i> Georgi Stems and Leaves Flavonoids in Promoting Neurogenesis and Improving Memory Impairment by the PI3K-AKT-CREB Signaling Pathway in Rats.

Liu, Qian-Qian; Ding, Sheng-Kai; Zhang, Hui; Shang, Ya-Zhen

The Molecular Mechanism of Scutellaria baicalensis Georgi Stems and Leaves Flavonoids in Promoting Neurogenesis and Improving Memory Impairment by the PI3K-AKT-CREB Signaling Pathway in Rats.

Liu, Qian-Qian; Ding, Sheng-Kai; Zhang, Hui; Shang, Ya-Zhen.

Afiliação

Liu QQ; Institute of Traditional Chinese Medicine, Chengde Medical College, Hebei Province Key Research Office of Traditional Chinese Medicine Against Dementia, Hebei Province Key Laboratory of Traditional Chinese Medicine Research and Development Hebei Key Laboratory of Nerve Injury and Repair, Chengde, He
Ding SK; Institute of Traditional Chinese Medicine, Chengde Medical College, Hebei Province Key Research Office of Traditional Chinese Medicine Against Dementia, Hebei Province Key Laboratory of Traditional Chinese Medicine Research and Development Hebei Key Laboratory of Nerve Injury and Repair, Chengde, He
Zhang H; Institute of Traditional Chinese Medicine, Chengde Medical College, Hebei Province Key Research Office of Traditional Chinese Medicine Against Dementia, Hebei Province Key Laboratory of Traditional Chinese Medicine Research and Development Hebei Key Laboratory of Nerve Injury and Repair, Chengde, He
Shang YZ; Institute of Traditional Chinese Medicine, Chengde Medical College, Hebei Province Key Research Office of Traditional Chinese Medicine Against Dementia, Hebei Province Key Laboratory of Traditional Chinese Medicine Research and Development Hebei Key Laboratory of Nerve Injury and Repair, Chengde, He

Comb Chem High Throughput Screen ; 25(5): 919-933, 2022.

Article em En | MEDLINE | ID: mdl-33966617

Assuntos

Doença de Alzheimer; Scutellaria baicalensis; Doença de Alzheimer/tratamento farmacológico; Peptídeos beta-Amiloides/efeitos adversos; Peptídeos beta-Amiloides/metabolismo; Animais; Modelos Animais de Doenças; Flavonoides/farmacologia; Masculino; Transtornos da Memória/tratamento farmacológico; Neurogênese; Fosfatidilinositol 3-Quinases/metabolismo; Folhas de Planta; Proteínas Proto-Oncogênicas c-akt/metabolismo; Ratos; Ratos Wistar; Scutellaria baicalensis/química; Scutellaria baicalensis/metabolismo; Transdução de Sinais

Palavras-chave

Alzheimer's disease; PI3K-AKT-CREB signaling pathway; Scutellaria baicalensis Georgi stems and leaves flavonoids; memory impairment; molecular mechanism; neurogenesis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Scutellaria baicalensis / Doença de Alzheimer Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Comb Chem High Throughput Screen Assunto da revista: BIOLOGIA MOLECULAR / QUIMICA Ano de publicação: 2022 Tipo de documento: Article

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