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Romidepsin (FK228) fails in counteracting the transformed phenotype of rhabdomyosarcoma cells but efficiently radiosensitizes, in vitro and in vivo, the alveolar phenotype subtype.
Rossetti, Alessandra; Petragnano, Francesco; Milazzo, Luisa; Vulcano, Francesca; Macioce, Giampiero; Codenotti, Silvia; Cassandri, Matteo; Pomella, Silvia; Cicchetti, Francesca; Fasciani, Irene; Antinozzi, Cristina; Di Luigi, Luigi; Festuccia, Claudio; De Felice, Francesca; Vergine, Massimo; Fanzani, Alessandro; Rota, Rossella; Maggio, Roberto; Polimeni, Antonella; Tombolini, Vincenzo; Gravina, Giovanni Luca; Marampon, Francesco.
Afiliação
  • Rossetti A; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
  • Petragnano F; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
  • Milazzo L; Department of Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.
  • Vulcano F; Department of Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.
  • Macioce G; Department of Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.
  • Codenotti S; Division of Biotechnology, Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
  • Cassandri M; Group of Epigenetics of Pediatric Sarcomas, Department of Oncohematology, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
  • Pomella S; Group of Epigenetics of Pediatric Sarcomas, Department of Oncohematology, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
  • Cicchetti F; Policlinico Umberto I Hospital, Roma, Italy.
  • Fasciani I; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
  • Antinozzi C; Unit of Endocrinology, Department of Movement, Human and Health Sciences, University of Rome "Foro Italico", Rome, Italy.
  • Di Luigi L; Unit of Endocrinology, Department of Movement, Human and Health Sciences, University of Rome "Foro Italico", Rome, Italy.
  • Festuccia C; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
  • De Felice F; Department of Radiotherapy, Policlinico Umberto I, "Sapienza" University of Rome, Rome, Italy.
  • Vergine M; Department of Surgical Sciences, "Sapienza" University of Rome, Rome, Italy.
  • Fanzani A; Division of Biotechnology, Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
  • Rota R; Group of Epigenetics of Pediatric Sarcomas, Department of Oncohematology, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
  • Maggio R; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
  • Polimeni A; Department of Oral and Maxillo-Facial Sciences, Sapienza University of Rome, Rome, Italy.
  • Tombolini V; Department of Radiotherapy, Policlinico Umberto I, "Sapienza" University of Rome, Rome, Italy.
  • Gravina GL; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
  • Marampon F; Department of Radiotherapy, Policlinico Umberto I, "Sapienza" University of Rome, Rome, Italy.
Int J Radiat Biol ; 97(7): 943-957, 2021.
Article em En | MEDLINE | ID: mdl-33979259

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenótipo / Radiossensibilizantes / Rabdomiossarcoma / Transformação Celular Neoplásica / Depsipeptídeos Limite: Animals / Humans Idioma: En Revista: Int J Radiat Biol Assunto da revista: RADIOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Itália

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenótipo / Radiossensibilizantes / Rabdomiossarcoma / Transformação Celular Neoplásica / Depsipeptídeos Limite: Animals / Humans Idioma: En Revista: Int J Radiat Biol Assunto da revista: RADIOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Itália