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Genetic variation affects morphological retinal phenotypes extracted from UK Biobank optical coherence tomography images.
Currant, Hannah; Hysi, Pirro; Fitzgerald, Tomas W; Gharahkhani, Puya; Bonnemaijer, Pieter W M; Senabouth, Anne; Hewitt, Alex W; Atan, Denize; Aung, Tin; Charng, Jason; Choquet, Hélène; Craig, Jamie; Khaw, Peng T; Klaver, Caroline C W; Kubo, Michiaki; Ong, Jue-Sheng; Pasquale, Louis R; Reisman, Charles A; Daniszewski, Maciej; Powell, Joseph E; Pébay, Alice; Simcoe, Mark J; Thiadens, Alberta A H J; van Duijn, Cornelia M; Yazar, Seyhan; Jorgenson, Eric; MacGregor, Stuart; Hammond, Chris J; Mackey, David A; Wiggs, Janey L; Foster, Paul J; Patel, Praveen J; Birney, Ewan; Khawaja, Anthony P.
Afiliação
  • Currant H; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Cambridge, United Kingdom.
  • Hysi P; School of Life Course Sciences, Section of Ophthalmology, King's College London, London, United Kingdom.
  • Fitzgerald TW; Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom.
  • Gharahkhani P; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Cambridge, United Kingdom.
  • Bonnemaijer PWM; Statistical Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
  • Senabouth A; Department of Ophthalmology, Erasmus MC, Rotterdam, The Netherlands.
  • Hewitt AW; Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands.
  • Atan D; Menzies Institute for Medical Research, School of Medicine, University of Tasmania, Tasmania, Australia.
  • Aung T; Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, East Melbourne, Australia.
  • Craig J; Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.
  • Khaw PT; Bristol Eye Hospital, University Hospitals Bristol & Weston NHS Foundation Trust, Bristol, United Kingdom.
  • Klaver CCW; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
  • Kubo M; Ophthalmology & Visual Sciences Academic Clinical Program, Duke-NUS Medical School, Singapore.
  • Ong JS; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
  • Pasquale LR; Centre for Ophthalmology and Visual Science, Lions Eye Institute, The University of Western Australia, Perth, Australia.
  • Reisman CA; Kaiser Permanente Northern California Division of Research, Oakland, California, United States of America.
  • Daniszewski M; Department of Ophthalmology, Flinders University, Flinders Medical Centre, Bedford Park, Australia.
  • Powell JE; NIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, United Kingdom.
  • Pébay A; Department of Ophthalmology, Erasmus MC, Rotterdam, The Netherlands.
  • Simcoe MJ; Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands.
  • Thiadens AAHJ; Department of Ophthalmology Radboud University Medical Center, Nijmegen, The Netherlands.
  • van Duijn CM; Institute of Molecular and Clinical Ophthalmology, Basel, Switzerland.
  • Yazar S; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
  • Jorgenson E; Statistical Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
  • MacGregor S; Eye and Vision Research Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.
  • Hammond CJ; Topcon Healthcare Solutions R&D, Oakland, New Jersey, United States of America.
  • Mackey DA; Department of Anatomy and Physiology, The University of Melbourne, Parkville, Australia.
  • Wiggs JL; Garvan Weizmann Centre for Cellular Genomics, Garvan Institute of Medical Research, The Kinghorn Cancer Centre, Darlinghurst, Australia.
  • Foster PJ; UNSW Cellular Genomics Futures Institute, University of New South Wales, Sydney, Australia.
  • Patel PJ; Department of Anatomy and Physiology, The University of Melbourne, Parkville, Australia.
  • Birney E; Department of Surgery, The University of Melbourne, Parkville, Australia.
  • Khawaja AP; Department of Ophthalmology, Kings College London, London, United Kingdom.
PLoS Genet ; 17(5): e1009497, 2021 05.
Article em En | MEDLINE | ID: mdl-33979322
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenótipo / Retina / Variação Genética / Bancos de Espécimes Biológicos / Tomografia de Coerência Óptica Tipo de estudo: Clinical_trials Limite: Female / Humans / Male / Middle aged País/Região como assunto: Europa Idioma: En Revista: PLoS Genet Assunto da revista: GENETICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenótipo / Retina / Variação Genética / Bancos de Espécimes Biológicos / Tomografia de Coerência Óptica Tipo de estudo: Clinical_trials Limite: Female / Humans / Male / Middle aged País/Região como assunto: Europa Idioma: En Revista: PLoS Genet Assunto da revista: GENETICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido